The emerging role of class-3 semaphorins and their neuropilin receptors in oncology
P Nasarre, RM Gemmill, HA Drabkin - OncoTargets and therapy, 2014 - Taylor & Francis
The semaphorins, discovered over 20 years ago, are a large family of secreted or
transmembrane and glycophosphatidylinositol-anchored proteins initially identified as axon …
transmembrane and glycophosphatidylinositol-anchored proteins initially identified as axon …
Semaphorin signaling in cancer cells and in cells of the tumor microenvironment–two sides of a coin
L Capparuccia, L Tamagnone - Journal of cell science, 2009 - journals.biologists.com
Semaphorins are a large family of secreted and membrane-bound molecules that were
initially implicated in the development of the nervous system and in axon guidance. More …
initially implicated in the development of the nervous system and in axon guidance. More …
Semaphorin signals on the road to cancer invasion and metastasis
S Rizzolio, L Tamagnone - Cell adhesion & migration, 2007 - Taylor & Francis
Semaphorins are a large family of secreted and membrane-bound molecules initially
implicated in the development of the nervous system and in axon guidance. More recently …
implicated in the development of the nervous system and in axon guidance. More recently …
Semaphorins and their receptors in lung cancer
VA Potiron, J Roche, HA Drabkin - Cancer letters, 2009 - Elsevier
Semaphorins are a large family of secreted, transmembrane and GPI-linked proteins initially
characterized in the development of the nervous system and axonal guidance. Semaphorins …
characterized in the development of the nervous system and axonal guidance. Semaphorins …
Semaphorins in cancer: biological mechanisms and therapeutic approaches
M Rehman, L Tamagnone - Seminars in cell & developmental biology, 2013 - Elsevier
The hallmarks of cancer include multiple alterations in the physiological processes occurring
in normal tissues, such as cell proliferation, apoptosis, and restricted cell migration. These …
in normal tissues, such as cell proliferation, apoptosis, and restricted cell migration. These …
The semaphorins: versatile regulators of tumour progression and tumour angiogenesis
G Neufeld, O Kessler - Nature Reviews Cancer, 2008 - nature.com
The semaphorins and their receptors, the neuropilins and the plexins, were originally
characterized as constituents of the complex regulatory system responsible for the guidance …
characterized as constituents of the complex regulatory system responsible for the guidance …
Semaphorin receptors meet receptor tyrosine kinases on the way of tumor progression
G Cagnoni, L Tamagnone - Oncogene, 2014 - nature.com
Semaphorins are extracellular signals known to guide migrating cells during developmental
morphogenesis and in adult tissues. Semaphorin receptors, that is plexins and neuropilins …
morphogenesis and in adult tissues. Semaphorin receptors, that is plexins and neuropilins …
[PDF][PDF] Semaphorins in cancer
G Neufeld, N Shraga-Heled, T Lange… - Front Biosci, 2005 - researchgate.net
The semaphorins are the products of a large family of genes currently containing more than
30 members. These genes are divided into eight classes of which classes 1, 2 and 8 contain …
30 members. These genes are divided into eight classes of which classes 1, 2 and 8 contain …
Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis
P Gaur, DR Bielenberg, S Samuel, D Bose, Y Zhou… - Clinical cancer …, 2009 - AACR
Abstract Class 3 semaphorins (SEMA3) were first identified as glycoproteins that negatively
mediate neuronal guidance by binding to neuropilin and repelling neurons away from the …
mediate neuronal guidance by binding to neuropilin and repelling neurons away from the …
The semaphorins and their receptors as modulators of tumor progression
G Neufeld, Y Mumblat, T Smolkin, S Toledano… - Drug Resistance …, 2016 - Elsevier
The semaphorins were initially characterized as repulsive axon guidance factors. However,
they are currently also recognized as important regulators of diverse biological processes …
they are currently also recognized as important regulators of diverse biological processes …