Mutations in neurexin and neuroligin genes have been associated with neurodevelopmental
disabilities including autism. Autism spectrum disorder is diagnosed by aberrant reciprocal …

NRXN1 microdeletions occur at a relatively high frequency and confer increased risk for
neurodevelopmental and neurobehavioral abnormalities. The mechanism that makes …

BACKGROUND:: Selective mutism (SM), considered an early-onset variant of social anxiety
disorder, shares features of impaired social interaction and communication with autism …

We generated human iPS derived neural stem cells and differentiated cells from healthy
control individuals and an individual with autism spectrum disorder carrying bi-allelic …

Hart characterizes a novel interaction between genetics and environmental stress on
experience-dependent neuron remodeling and plasticity in Caenorhabditis elegans …

A number of genetic studies have identified rare protein-coding DNA variations associated
with autism spectrum disorder (ASD), a neurodevelopmental disorder with significant …

Abstract 2p16. 3 deletions, involving heterozygous NEUREXIN1 (NRXN1) deletion,
dramatically increase the risk of developing neurodevelopmental disorders, including autism …

In our previous study, we screened autism spectrum disorder (ASD) patients with and
without sleep disorders for mutations in the coding regions of circadian-relevant genes, and …

Neurexins are a family of presynaptic cell adhesion proteins that regulate synaptic structure
and maintain normal synaptic transmission. Mutations in the α-isoform of neurexin1-gene …

Autism is a genetically complex neurodevelopmental syndrome in which language deficits
are a core feature. We describe results from two complimentary approaches used to identify …