Effect of genetic architecture on the prediction accuracy of quantitative traits in samples of unrelated individuals
Predicting complex phenotypes from genomic data is a fundamental aim of animal and plant
breeding, where we wish to predict genetic merits of selection candidates; and of human …
breeding, where we wish to predict genetic merits of selection candidates; and of human …
Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster
SM Edwards, IF Sørensen, P Sarup, TFC Mackay… - Genetics, 2016 - academic.oup.com
Predicting individual quantitative trait phenotypes from high-resolution genomic
polymorphism data is important for personalized medicine in humans, plant and animal …
polymorphism data is important for personalized medicine in humans, plant and animal …
Integrating nonadditive genomic relationship matrices into the study of genetic architecture of complex traits
A Nazarian, SA Gezan - Journal of Heredity, 2016 - academic.oup.com
The study of genetic architecture of complex traits has been dramatically influenced by
implementing genome-wide analytical approaches during recent years. Of particular interest …
implementing genome-wide analytical approaches during recent years. Of particular interest …
Epistasis: obstacle or advantage for mapping complex traits?
KJF Verhoeven, G Casella, LM McIntyre - PloS one, 2010 - journals.plos.org
Identification of genetic loci in complex traits has focused largely on one-dimensional
genome scans to search for associations between single markers and the phenotype. There …
genome scans to search for associations between single markers and the phenotype. There …
Improving accuracy of genomic prediction by genetic architecture based priors in a Bayesian model
N Gao, J Li, J He, G Xiao, Y Luo, H Zhang, Z Chen… - BMC genetics, 2015 - Springer
Background In recent years, with the development of high-throughput sequencing
technology and the commercial availability of genotyping bead chips, more attention is …
technology and the commercial availability of genotyping bead chips, more attention is …
Using genetic distance to infer the accuracy of genomic prediction
The prediction of phenotypic traits using high-density genomic data has many applications
such as the selection of plants and animals of commercial interest; and it is expected to play …
such as the selection of plants and animals of commercial interest; and it is expected to play …
GenoMatrix: a software package for pedigree-based and genomic prediction analyses on complex traits
A Nazarian, SA Gezan - Journal of Heredity, 2016 - academic.oup.com
Genomic and pedigree-based best linear unbiased prediction methodologies (G-BLUP and
P-BLUP) have proven themselves efficient for partitioning the phenotypic variance of …
P-BLUP) have proven themselves efficient for partitioning the phenotypic variance of …
Impact of linkage disequilibrium heterogeneity along the genome on genomic prediction and heritability estimation
D Ren, X Cai, Q Lin, H Ye, J Teng, J Li, X Ding… - Genetics Selection …, 2022 - Springer
Background Compared to medium-density single nucleotide polymorphism (SNP) data, high-
density SNP data contain abundant genetic variants and provide more information for the …
density SNP data contain abundant genetic variants and provide more information for the …
Genome-wide prediction of traits with different genetic architecture through efficient variable selection
In genome-based prediction there is considerable uncertainty about the statistical model
and method required to maximize prediction accuracy. For traits influenced by a small …
and method required to maximize prediction accuracy. For traits influenced by a small …
Empirical and deterministic accuracies of across-population genomic prediction
Background Differences in linkage disequilibrium and in allele substitution effects of QTL
(quantitative trait loci) may hinder genomic prediction across populations. Our objective was …
(quantitative trait loci) may hinder genomic prediction across populations. Our objective was …
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