The field of regenerative engineering relies primarily on the dual technical platforms of cell
selection/conditioning and biomaterial fabrication to support directed cell differentiation. As …

Proper tissue function and regeneration rely on robust spatial and temporal control of
biophysical and biochemical microenvironmental cues through mechanisms that remain …

The spacing of hair in mammals and feathers in birds is one of the most apparent
morphological features of the skin. This pattern arises when uniform fields of progenitor cells …

The living cell is an incredibly complex entity, and the goal of predictively and quantitatively
understanding its function is one of the next great challenges in biology. Much of what we …

Biological patterns emerge through specialization of genetically identical cells to take up
distinct fates according to their position within the organism. How initial symmetry is broken …

The structural and functional complexity of multicellular biological systems, such as the
brain, are beyond the reach of human design or assembly capabilities. Cells in living …

During organogenesis, various molecular and physical signals are orchestrated in space
and time to sculpt multiple cell types into functional tissues and organs. The complex and …

Organogenesis and morphogenesis have informed our understanding of physiology,
pathophysiology, and avenues to create new curative and regenerative therapies. Thus far …

The ability of stem cells to differentiate into specified lineages in the appropriate locations is
vital to morphogenesis and adult tissue regeneration. Although soluble signals are important …

Monitoring of cell-cell communication in multicellular organisms is fundamental to
understanding diverse biological processes such as embryogenesis and tumorigenesis. To …