Tumour necrosis factor-α (TNF-α) plays a key role in orchestrating the complex events
involved in inflammation and immunity. Accordingly, TNF-α has been implicated in a wide …

Tumor necrosis factor-alpha (TNF-α) is a potent immunomediator and proinflammatory
cytokine that has been implicated in the pathogenesis of a large number of human diseases …

Tumor necrosis factor α (TNFα) is a potent inflammatory cytokine. In human, the TNFα gene
is located within the highly polymorphic major histocompatibility complex (MHC) region on …

Tumour necrosis factor (TNF), an important proinflammatory cytokine, plays a role in the
regulation of cell differentiation, proliferation and death, as well as in inflammation, innate …

Since a dysregulated synthesis of tumor necrosis factor alpha (TNF-alpha) may be involved
in the pathogenesis of autoimmune diseases, it was of interest to precisely locate the …

Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine with an important role in
the pathogenesis of several diseases. Its encoding gene is located in the short arm of …

Polymorphism of the 5′‐flanking promoter/enhancer region of the TNF‐α gene in Japanese
is not well understood. To better understand it, we have determined the 1,358 base pair …

4. Kaijzel EL, Bayley JP, Smith L, Van de Linde P, Bakker AM, Verweij CL Allele-specific
quantification of tumour necrosis factor alpha transcription and the role of promoter …

Tumour necrosis factor-alpha (TNF-alpha) is a potent immunomediator and proinflammatory
cytokine that has been implicated in the pathogenesis of a large number of human diseases …

Interindividual variation in the expression of tumor necrosis factor α (TNF) suggests the
existence of functionally distinct TNF alleles that could play a role in susceptibility to TNF …