The phylogenetic diversity of metagenomes

SW Kembel, JA Eisen, KS Pollard, JL Green - PLoS One, 2011 - journals.plos.org
Phylogenetic diversity—patterns of phylogenetic relatedness among organisms in
ecological communities—provides important insights into the mechanisms underlying …

Toward an efficient method of identifying core genes for evolutionary and functional microbial phylogenies

N Segata, C Huttenhower - PloS one, 2011 - journals.plos.org
Microbial community metagenomes and individual microbial genomes are becoming
increasingly accessible by means of high-throughput sequencing. Assessing organismal …

Environmental atlas of prokaryotes enables powerful and intuitive habitat-based analysis of community structures

K Mise, W Iwasaki - Iscience, 2020 - cell.com
The recent prevalence of high-throughput sequencing has been producing numerous
prokaryotic community structure datasets. Although the trait-based approach is useful to …

Population genomics in natural microbial communities

RJ Whitaker, JF Banfield - Trends in Ecology & Evolution, 2006 - cell.com
Little is known about the evolutionary processes that structure and maintain microbial
diversity because, until recently, it was difficult to explore individual-level patterns of …

Quantitative metagenomic analyses based on average genome size normalization

JA Frank, SJ Sørensen - Applied and environmental microbiology, 2011 - Am Soc Microbiol
Over the past quarter-century, microbiologists have used DNA sequence information to aid
in the characterization of microbial communities. During the last decade, this has expanded …

Challenges and opportunities in understanding microbial communities with metagenome assembly (accompanied by IPython Notebook tutorial)

A Howe, PSG Chain - Frontiers in microbiology, 2015 - frontiersin.org
Metagenomic investigations hold great promise for informing the genetics, physiology, and
ecology of environmental microorganisms. Current challenges for metagenomic analysis are …

A metagenomic assessment of microbial eukaryotic diversity in the global ocean

A Obiol, CR Giner, P Sánchez… - Molecular Ecology …, 2020 - Wiley Online Library
Surveying microbial diversity and function is accomplished by combining complementary
molecular tools. Among them, metagenomics is a PCR free approach that contains all …

Phylogeny-based classification of microbial communities

O Tanaseichuk, J Borneman, T Jiang - Bioinformatics, 2014 - academic.oup.com
Motivation: Next-generation sequencing coupled with metagenomics has led to the rapid
growth of sequence databases and enabled a new branch of microbiology called …

Strainer: software for analysis of population variation in community genomic datasets

JM Eppley, GW Tyson, WM Getz, JF Banfield - BMC bioinformatics, 2007 - Springer
Background Metagenomic analyses of microbial communities that are comprehensive
enough to provide multiple samples of most loci in the genomes of the dominant organism …

Computational methods for high-throughput comparative analyses of natural microbial communities

SP Preheim, AR Perrotta, J Friedman, C Smilie… - Methods in …, 2013 - Elsevier
One of the most widely employed methods in metagenomics is the amplification and
sequencing of the highly conserved ribosomal RNA (rRNA) genes from organisms in …