The phylogenetic diversity of metagenomes
Phylogenetic diversity—patterns of phylogenetic relatedness among organisms in
ecological communities—provides important insights into the mechanisms underlying …
ecological communities—provides important insights into the mechanisms underlying …
Toward an efficient method of identifying core genes for evolutionary and functional microbial phylogenies
N Segata, C Huttenhower - PloS one, 2011 - journals.plos.org
Microbial community metagenomes and individual microbial genomes are becoming
increasingly accessible by means of high-throughput sequencing. Assessing organismal …
increasingly accessible by means of high-throughput sequencing. Assessing organismal …
Environmental atlas of prokaryotes enables powerful and intuitive habitat-based analysis of community structures
The recent prevalence of high-throughput sequencing has been producing numerous
prokaryotic community structure datasets. Although the trait-based approach is useful to …
prokaryotic community structure datasets. Although the trait-based approach is useful to …
Population genomics in natural microbial communities
RJ Whitaker, JF Banfield - Trends in Ecology & Evolution, 2006 - cell.com
Little is known about the evolutionary processes that structure and maintain microbial
diversity because, until recently, it was difficult to explore individual-level patterns of …
diversity because, until recently, it was difficult to explore individual-level patterns of …
Quantitative metagenomic analyses based on average genome size normalization
JA Frank, SJ Sørensen - Applied and environmental microbiology, 2011 - Am Soc Microbiol
Over the past quarter-century, microbiologists have used DNA sequence information to aid
in the characterization of microbial communities. During the last decade, this has expanded …
in the characterization of microbial communities. During the last decade, this has expanded …
Challenges and opportunities in understanding microbial communities with metagenome assembly (accompanied by IPython Notebook tutorial)
Metagenomic investigations hold great promise for informing the genetics, physiology, and
ecology of environmental microorganisms. Current challenges for metagenomic analysis are …
ecology of environmental microorganisms. Current challenges for metagenomic analysis are …
A metagenomic assessment of microbial eukaryotic diversity in the global ocean
Surveying microbial diversity and function is accomplished by combining complementary
molecular tools. Among them, metagenomics is a PCR free approach that contains all …
molecular tools. Among them, metagenomics is a PCR free approach that contains all …
Phylogeny-based classification of microbial communities
Motivation: Next-generation sequencing coupled with metagenomics has led to the rapid
growth of sequence databases and enabled a new branch of microbiology called …
growth of sequence databases and enabled a new branch of microbiology called …
Strainer: software for analysis of population variation in community genomic datasets
Background Metagenomic analyses of microbial communities that are comprehensive
enough to provide multiple samples of most loci in the genomes of the dominant organism …
enough to provide multiple samples of most loci in the genomes of the dominant organism …
Computational methods for high-throughput comparative analyses of natural microbial communities
SP Preheim, AR Perrotta, J Friedman, C Smilie… - Methods in …, 2013 - Elsevier
One of the most widely employed methods in metagenomics is the amplification and
sequencing of the highly conserved ribosomal RNA (rRNA) genes from organisms in …
sequencing of the highly conserved ribosomal RNA (rRNA) genes from organisms in …