Endocannabinoids in the treatment of gastrointestinal inflammation and symptoms

M Pesce, G Esposito, G Sarnelli - Current Opinion in Pharmacology, 2018 - Elsevier
Highlights•The use of Cannabis as a complementary and alternative medicine in
inflammatory bowel disease has increased due to the evolving policies regarding its …

The role of cannabinoids in regulation of nausea and vomiting, and visceral pain

Z Malik, D Baik, R Schey - Current Gastroenterology Reports, 2015 - Springer
Marijuana derived from the plant Cannabis sativa has been used for the treatment of many
gastrointestinal (GI) disorders, including anorexia, emesis, abdominal pain, diarrhea, and …

The endocannabinoid system and gut–brain signalling

MA Storr, KA Sharkey - Current opinion in pharmacology, 2007 - Elsevier
The endocannabinoid system (ECS) consists of cannabinoid receptors, endogenous ligands
and the biosynthetic and metabolic enzymes for their formation and degradation. Within the …

Cannabis, cannabinoids, and the endocannabinoid system—is there therapeutic potential for inflammatory bowel disease?

T Ambrose, A Simmons - Journal of Crohn's and Colitis, 2019 - academic.oup.com
Cannabis sativa and its extracts have been used for centuries, both medicinally and
recreationally. There is accumulating evidence that exogenous cannabis and related …

Endocannabinoid overactivity and intestinal inflammation

V Di Marzo, AA Izzo - Gut, 2006 - gut.bmj.com
Cannabinoid receptors of type 1 and 2 (CB1 and CB2), endogenous ligands that activate
them (endocannabinoids), and mechanisms for endocannabinoid biosynthesis and …

Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases

R Schicho, M Storr - Canadian Journal of Gastroenterology and …, 2011 - Wiley Online Library
Many beneficial effects of herbal and synthetic cannabinoids on gut motility and
inflammation have been demonstrated, suggesting a vast potential for these compounds in …

Cannabinoids and the gut: new developments and emerging concepts

AA Izzo, KA Sharkey - Pharmacology & therapeutics, 2010 - Elsevier
Cannabis has been used to treat gastrointestinal (GI) conditions that range from enteric
infections and inflammatory conditions to disorders of motility, emesis and abdominal pain …

[HTML][HTML] Role of cannabis in inflammatory bowel diseases

A Perisetti, AH Rimu, SA Khan, P Bansal… - Annals of …, 2020 - ncbi.nlm.nih.gov
For many centuries, cannabis (marijuana) has been used for both recreational and
medicinal purposes. Currently, there are about 192 million cannabis users worldwide …

Manipulation of the endocannabinoid system in colitis: a comprehensive review

KL Leinwand, ME Gerich, EJ Hoffenberg… - Inflammatory bowel …, 2017 - academic.oup.com
Background Inflammatory bowel disease (IBD) is a lifelong disease of the gastrointestinal
tract whose annual incidence and prevalence is on the rise. Current immunosuppressive …

Effects of cannabidiol chewing gum on perceived pain and well-being of irritable bowel syndrome patients: a placebo-controlled crossover exploratory intervention …

ACB van Orten-Luiten, NM De Roos… - Cannabis and …, 2022 - liebertpub.com
Background: Irritable bowel syndrome (IBS) is one of the most common gastrointestinal
disorders. Its pathophysiology is diverse and variable, involving disturbed gut–brain …