Endocannabinoid‐related compounds in gastrointestinal diseases

M Pesce, A D'Alessandro, O Borrelli… - Journal of cellular …, 2018 - Wiley Online Library
The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the
control of several gastrointestinal (GI) functions at both peripheral and central levels. In …

Endocannabinoids and their receptors in the enteric nervous system

M Duncan, JS Davison… - Alimentary pharmacology …, 2005 - Wiley Online Library
The therapeutic actions of cannabinoids have been known for centuries. In the last 25 years
this area of research has grown exponentially with the discovery of specific cannabinoid …

Cannabinoid signalling regulates inflammation and energy balance: the importance of the brain–gut axis

NL Cluny, RA Reimer, KA Sharkey - Brain, behavior, and immunity, 2012 - Elsevier
Energy balance is controlled by centres of the brain which receive important inputs from the
gastrointestinal tract, liver, pancreas, adipose tissue and skeletal muscle, mediated by many …

Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go?

C Hasenoehrl, M Storr, R Schicho - Expert review of …, 2017 - Taylor & Francis
Introduction: Fifty years after the discovery of Δ9-tetrahydrocannabinol (THC) as the
psychoactive component of Cannabis, we are assessing the possibility of translating this …

Cannabinoids cool the intestine

G Kunos, P Pacher - Nature medicine, 2004 - nature.com
Cannabinoids cool the intestine | Nature Medicine Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Role of cannabinoid receptors in the control of gastrointestinal motility and perception

J Fioramonti, L Bueno - Expert review of gastroenterology & …, 2008 - Taylor & Francis
The identification of endocannabinoids and cannabinoid CB1 receptors in key areas of the
intestinal wall, such as cholinergic neurons, supports a role for cannabinoids in the control of …

Cannabinoids for gastrointestinal diseases: potential therapeutic applications

GD Carlo, AA Izzo - Expert opinion on investigational drugs, 2003 - Taylor & Francis
Δ9-Tetrahydrocannabinol (the active ingredient of marijuana), as well as endogenous and
synthetic cannabinoids, exert many biological functions by activating two types of …

The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity

M Alhouayek, GG Muccioli - Trends in molecular medicine, 2012 - cell.com
Crohn's disease and ulcerative colitis are two major forms of inflammatory bowel diseases
(IBD), which are chronic inflammatory disorders of the gastrointestinal tract. These …

The endocannabinoid system and its role in regulating the intrinsic neural circuitry of the gastrointestinal tract

SM Trautmann, KA Sharkey - International review of neurobiology, 2015 - Elsevier
Endocannabinoids are important neuromodulators in the central nervous system. They
regulate central transmission through pre-and postsynaptic actions on neurons and …

Endocannabinoids in the gastrointestinal tract

Y Lee, J Jo, HY Chung… - American Journal of …, 2016 - journals.physiology.org
The endocannabinoid system mainly consists of endogenously produced cannabinoids
(endocannabinoids) and two G protein-coupled receptors (GPCRs), cannabinoid receptors …