Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is broadly accepted that SARS …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is broadly accepted that SARS …
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
R Yan, Y Zhang, Y Li, L Xia, Y Guo, Q Zhou - Science, 2020 - science.org
Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for severe acute respiratory
syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing …
syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing …
A novel soluble ACE2 protein provides lung and kidney protection in mice susceptible to lethal SARS-CoV-2 infection
L Hassler, J Wysocki, I Gelarden, I Sharma… - Journal of the …, 2022 - journals.lww.com
Background Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) uses full-
length angiotensin converting enzyme 2 (ACE2) as a main receptor to enter target cells. The …
length angiotensin converting enzyme 2 (ACE2) as a main receptor to enter target cells. The …
Role of ACE2 receptor and the landscape of treatment options from convalescent plasma therapy to the drug repurposing in COVID-19
Since the first case reports in Wuhan, China, the SARS-CoV-2 has caused a pandemic and
took lives of> 8, 35,000 people globally. This single-stranded RNA virus uses Angiotensin …
took lives of> 8, 35,000 people globally. This single-stranded RNA virus uses Angiotensin …
COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection
S Beyerstedt, EB Casaro, ÉB Rangel - European journal of clinical …, 2021 - Springer
COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …
Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences
Coronavirus disease 2019 (COVID-19) causes persistent endothelial inflammation, lung,
cardiovascular, kidney and neurological complications, and thromboembolic phenomena of …
cardiovascular, kidney and neurological complications, and thromboembolic phenomena of …
Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
ME Ortiz, A Thurman, AA Pezzulo, MR Leidinger… - …, 2020 - thelancet.com
Background Zoonotically transmitted coronaviruses are responsible for three disease
outbreaks since 2002, including the current COVID-19 pandemic, caused by SARS-CoV-2 …
outbreaks since 2002, including the current COVID-19 pandemic, caused by SARS-CoV-2 …
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection
Abstract Angiotensin-converting enzyme 2 (ACE2) is the main entry point in airway epithelial
cells for SARS-CoV-2. ACE2 binding to the SARS-CoV-2 protein spike triggers viral fusion …
cells for SARS-CoV-2. ACE2 binding to the SARS-CoV-2 protein spike triggers viral fusion …
Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects
M Jacobs, HP Van Eeckhoutte… - European …, 2020 - Eur Respiratory Soc
Angiotensin-converting enzyme 2 (ACE2) has been identified as the cell entry receptor used
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1, 2]. Importantly …
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1, 2]. Importantly …
ACE2 and COVID-19 and the resulting ARDS
X Zhang, S Li, S Niu - Postgraduate medical journal, 2020 - academic.oup.com
This article reviews the correlation between ACE2 and COVID-19 and the resulting acute
respiratory distress syndrome (ARDS). ACE2 is a crucial component of the renin-angiotensin …
respiratory distress syndrome (ARDS). ACE2 is a crucial component of the renin-angiotensin …