Geographic distribution, clinical epidemiology and genetic diversity of the human oncogenic retrovirus HTLV-1 in Africa, the world's largest endemic area

A Gessain, JL Ramassamy, PV Afonso… - Frontiers in …, 2023 - frontiersin.org
The African continent is considered the largest high endemic area for the oncogenic
retrovirus HTLV-1 with an estimated two to five million infected individuals. However, data on …

Human retrovirus HTLV-1: descriptive and molecular epidemiology, origin, evolution, diagnosis and associated diseases

A Gessain - Bulletin de la Societe de pathologie exotique, 2011 - Springer
Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) was the first oncogenic human
retrovirus discovered in 1980. It is estimated that around 10–20 million people are infected …

Comparative seroepidemiology of HTLV-I and HTLV-III in the French West Indies and some African countries

G De-The, A Gessain, L Gazzolo, M Robert-Guroff… - Cancer research, 1985 - AACR
The prevalence of antibodies detected by ELISA against human T-lymphotropic viruses, type
I (HTLV-I) and type III (HTLV-III-LAV), is described in a comparative serosurvey in the French …

The human HTLV-3 and HTLV-4 retroviruses: new members of the HTLV family

R Mahieux, A Gessain - Pathologie Biologie, 2009 - Elsevier
Human T cell leukemia/lymphoma virus Type 1 and 2 (HTLV-1 and HTLV-2), together with
their simian counterparts (STLV-1, STLV-2), belong to the Primate T lymphotropic viruses …

Epidemiological aspects and world distribution of HTLV-1 infection

A Gessain, O Cassar - Frontiers in microbiology, 2012 - frontiersin.org
The human T-cell leukemia virus type 1 (HTLV-1), identified as the first human oncogenic
retrovirus 30 years ago, is not an ubiquitous virus. HTLV-1 is present throughout the world …

Comparative virology of HTLV-1 and HTLV-2

MP Martinez, J Al-Saleem, PL Green - Retrovirology, 2019 - Springer
Human T cell leukemia virus type 1 (HTLV-1) was the first discovered human retrovirus and
the etiologic agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropical …

The challenge of describing the epidemiology of HTLV in the Amazon region of Brazil

R Ishak, M de Oliveira Guimarães Ishak, ACR Vallinoto - Retrovirology, 2020 - Springer
HTLV-1 was the first described human retrovirus and was soon found to be associated with
severe clinical diseases, including a devastating lymphoma/leukemia and other …

Time to eradicate HTLV-1: an open letter to WHO

F Martin, Y Tagaya, R Gallo - The Lancet, 2018 - thelancet.com
Human T-cell leukaemia virus 1 (HTLV-1) is the most potent carcinogenic oncovirus and
potentially the most oncogenic risk factor including chem ical carcinogens. 1 A unique and …

Epidemiology, origin and genetic diversity of HTLV-1 retrovirus and STLV-1 simian affiliated retrovirus

A Gessain, R Mahieux - Bulletin de la Societe de Pathologie …, 2000 - europepmc.org
Human T Cell leukemia/lymphoma virus type I, the first human oncogenic retrovirus, is the
aetiological factor of Adult T cell leukemia (ATL), a CD4+ malignant lymphoproliferative …

Molecular epidemiology, genetic variability and evolution of HTLV-1 with special emphasis on African genotypes

PV Afonso, O Cassar, A Gessain - Retrovirology, 2019 - Springer
Human T cell leukemia virus (HTLV-1) is an oncoretrovirus that infects at least 10 million
people worldwide. HTLV-1 exhibits a remarkable genetic stability, however, viral strains …