Surgery is potentially curative for primary nonmetastatic extremity soft tissue sarcomas. After
surgery alone, patients may remain at risk for local recurrences and/or metastatic disease …

Opinion statement High-risk soft tissue sarcomas (STS) are defined as large (> 5 cm),
intermediate/high-grade tumors and can carry a> 50% risk of death from metastases. A …

Management of extremity soft tissue sarcomas with limb-sparing surgery and postoperative
irradiation: do total dose, overall treatment time, and the surgery-radiotherapy interval …

Background This update of a randomized, prospective study presents the effect of external
beam radiation therapy (EBRT) on long-term overall survival, local control, and limb function …

Background The role of radiotherapy (RTx) and chemotherapy (CTx) in primary extremity
soft tissue sarcoma (eSTS) patients is not precisely defined. Methods All consecutive …

The traditional approach to extremity sarcomas was surgical excision. This was associated
with a local failure rate of approximately 95%[1], as tumors were simply'shelled out'of their …

Opinion statement For localized extremity soft tissue sarcoma (eSTS), treatment is
individualized and each patient needs to be evaluated by a multidisciplinary team at a …

Opinion statement When treating soft tissue sarcomas (STS) of the extremities, the major
therapeutic goals are survival, local tumor control, optimal function, and minimal morbidity …

Background: Substantial progress has been made in the multimodality treatment of soft
tissue sarcoma over the past decade. This review summarizes current state-of-the-art …

Abstract Background and Objectives Modern series of adult extremity soft tissue sarcomas
utilize combinations of modalities in all patients. Remaining questions: 1) is it necessary to …