Interrupting rituximab treatment in relapsing-remitting multiple sclerosis; no evidence of rebound disease activity
A Juto, K Fink, F Al Nimer, F Piehl - Multiple sclerosis and related disorders, 2020 - Elsevier
Background Rituximab (RTX) and other anti-CD20 therapies are increasingly used as
disease modifying treatments (DMTs) in MS. However, data on reasons to interrupt …
disease modifying treatments (DMTs) in MS. However, data on reasons to interrupt …
Efficacy of rituximab in refractory RRMS
P Durozard, A Maarouf, C Boutiere… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Objective: To investigate the efficacy of rituximab as rescue therapy in patients with
relapsing-remitting multiple sclerosis (RRMS) and persistent disease activity confirmed by …
relapsing-remitting multiple sclerosis (RRMS) and persistent disease activity confirmed by …
[HTML][HTML] Efficacy and safety of repeated low-dose rituximab therapy in relapsing-remitting multiple sclerosis: A retrospective case series study
D Zhao, C Zhao, J Lu, Y Han, T Sun, K Ren… - Multiple Sclerosis and …, 2023 - Elsevier
Background Rituximab (RTX) is an extensively used off-label drug for multiple sclerosis
(MS), whereas the induction and maintenance regimens vary widely among studies. Few …
(MS), whereas the induction and maintenance regimens vary widely among studies. Few …
Discontinuation and dose reduction of rituximab in relapsing–remitting multiple sclerosis
M Boremalm, P Sundström, J Salzer - Journal of Neurology, 2021 - Springer
Background Rituximab is safe and effective for treating relapsing–remitting multiple sclerosis
(RRMS) according to phase II and observational studies. There are limited data on disease …
(RRMS) according to phase II and observational studies. There are limited data on disease …
Safety and efficacy of rituximab as first-and second line treatment in multiple sclerosis–A cohort study
HM Torgauten, KM Myhr, S Wergeland… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background Rituximab is increasingly used as off-label therapy in multiple sclerosis (MS).
More data are needed on safety and efficacy of rituximab, particularly in cohorts of de novo …
More data are needed on safety and efficacy of rituximab, particularly in cohorts of de novo …
Improved treatment satisfaction after switching therapy to rituximab in relapsing–remitting MS
P de Flon, K Laurell, L Söderström… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Objective: New disease-modifying treatment strategies in multiple sclerosis offer possibilities
for individualised treatment. In this study, we evaluated patient-reported outcome measures …
for individualised treatment. In this study, we evaluated patient-reported outcome measures …
Rituximab in relapsing and progressive forms of multiple sclerosis: a systematic review
T Castillo-Trivino, D Braithwaite, P Bacchetti… - PloS one, 2013 - journals.plos.org
Background Rituximab is an anti-CD20 monoclonal antibody approved for non Hodgkin
lymphoma and rheumatoid arthritis. It is being considered for the treatment of MS. Objectives …
lymphoma and rheumatoid arthritis. It is being considered for the treatment of MS. Objectives …
Comparative effectiveness of rituximab and other initial treatment choices for multiple sclerosis
M Granqvist, M Boremalm, A Poorghobad… - JAMA …, 2018 - jamanetwork.com
Importance Comparative real-world effectiveness studies of initial disease-modifying
treatment (DMT) choices for relapsing-remitting multiple sclerosis (RRMS) that include …
treatment (DMT) choices for relapsing-remitting multiple sclerosis (RRMS) that include …
Long-term B-lymphocyte depletion with rituximab in patients with relapsing-remitting multiple sclerosis
Objective To describe 2 patients with relapsing-remitting multiple sclerosis (RRMS)
receiving long-term treatment with the monoclonal antibody rituximab. The clinical and …
receiving long-term treatment with the monoclonal antibody rituximab. The clinical and …
Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: a 52-week phase II trial
Objective: B cells and the humoral immune system have been implicated in the
pathogenesis of multiple sclerosis (MS). This study sought to evaluate the efficacy, safety …
pathogenesis of multiple sclerosis (MS). This study sought to evaluate the efficacy, safety …