Results of genome-wide linkage analyses to identify chromosomal regions that influence
interindividual variation in plasma lipid and apolipoprotein levels in the Rochester, Minn …

Although a considerable proportion of serum lipids loci identified in European ancestry
individuals (EA) replicate in African Americans (AA), interethnic differences in the distribution …

Abstract Background Lipoprotein (a)(Lp (a)) is recognized as a causal factor for coronary
heart disease (CHD) but its atherogenicity relative to that of low-density lipoprotein (LDL) on …

While conventional LDL-C, HDL-C, and triglyceride measurements reflect aggregate
properties of plasma lipoprotein fractions, NMR-based measurements more accurately …

To identify genetic variants influencing plasma lipid concentrations, we first used genotype
imputation and meta-analysis to combine three genome-wide scans totaling 8,816 …

Blood lipids are heritable modifiable causal factors for coronary artery disease. Despite well-
described monogenic and polygenic bases of dyslipidemia, limitations remain in discovery …

Plasma lipoprotein concentrations are associated with risk of coronary artery disease, a
leading cause of mortality and morbidity worldwide. Three new genome-wide association …

This study reviews ancestral differences in the genetics of the LPA gene, risk categories of
elevated lipoprotein (a)[Lp (a)] as defined by guidelines, ancestry-specific Lp (a) risk …

Levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL)
cholesterol, triglycerides and total cholesterol are heritable, modifiable risk factors for …

Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers
potential advantages for locus discovery. We perform WGS in 16,324 participants from four …