Abstract P2-13-04: Inclusion of Patients with Leptomeningeal Disease in Phase III Randomized Clinical Trials of Patients with Advanced Breast Cancer, Lung Cancer …
Introduction: Leptomeningeal disease (LMD) is a late complication of metastatic cancer that
significantly limits patient survival. LMD is most prevalent in patients with melanoma, lung …
significantly limits patient survival. LMD is most prevalent in patients with melanoma, lung …
Clinical factors and association with treatment modalities in patients with breast cancer and brain metastases who develop leptomeningeal metastases
A Puri, C Mylavarapu, J Xu, TA Patel, B S. Teh… - Breast Cancer Research …, 2022 - Springer
Purpose Leptomeningeal metastases (LM) are an aggressive complication of metastatic
breast cancer (MBC) with brain metastases (BM), with a short survival of weeks to months …
breast cancer (MBC) with brain metastases (BM), with a short survival of weeks to months …
Breast leptomeningeal disease: a review of current practices and updates on management
NB Figura, VT Rizk, AJ Armaghani, JA Arrington… - Breast Cancer Research …, 2019 - Springer
Purpose Leptomeningeal disease (LMD) is an advanced metastatic disease presentation
portending a poor prognosis with minimal treatment options. The advent and widespread …
portending a poor prognosis with minimal treatment options. The advent and widespread …
Clinicopathological features of breast cancers predict the development of leptomeningeal metastases: a case-control study
E Le Rhun, S Taillibert, F Zairi, P Devos… - Journal of neuro …, 2011 - Springer
The incidence of leptomeningeal metastases (LM) in patients with breast cancer (BC) is
increasing as a result of increased screening and improved patient survival. However, the …
increasing as a result of increased screening and improved patient survival. However, the …
Neratinib and capecitabine for the treatment of leptomeningeal metastases from HER2-positive breast cancer: a series in the setting of a compassionate program
A Pellerino, R Soffietti, F Bruno, R Manna, E Muscolino… - Cancers, 2022 - mdpi.com
Simple Summary Leptomeningeal metastases represent an unmet need due to the lack of
effective therapy and poor survival. The tyrosine kinase inhibitor, neratinib, has …
effective therapy and poor survival. The tyrosine kinase inhibitor, neratinib, has …
Systemic treatment for brain metastasis and Leptomeningeal disease in breast cancer patients
Abstract Purpose of Review Breast cancer with brain metastasis (BCBM) and
leptomeningeal disease (LMD) are important clinical problems. Traditionally, patients with …
leptomeningeal disease (LMD) are important clinical problems. Traditionally, patients with …
[图书][B] Leptomeningeal metastases
LE Abrey, M Chamberlain, H Engelhard - 2005 - books.google.com
Leptomeningeal Metastases is intended to provide the reader with an overview of the state-
of-the-art therapy for the cancer patient with leptomeningeal cancer with additional …
of-the-art therapy for the cancer patient with leptomeningeal cancer with additional …
[HTML][HTML] How we treat patients with leptomeningeal metastases
E Le Rhun, M Preusser, M van den Bent… - ESMO open, 2019 - Elsevier
The goal of treatment of leptomeningeal metastasis is to improve survival and to maintain
quality of life by delaying neurological deterioration. Tumour-specific therapeutic options …
quality of life by delaying neurological deterioration. Tumour-specific therapeutic options …
Intrathecal liposomal cytarabine plus systemic therapy versus systemic chemotherapy alone for newly diagnosed leptomeningeal metastasis from breast cancer
E Le Rhun, J Wallet, A Mailliez, MC Le Deley… - Neuro …, 2020 - academic.oup.com
Background DEPOSEIN (NCT01645839) was a randomized open-label phase III study to
explore the role of intrathecal chemotherapy in patients with newly diagnosed …
explore the role of intrathecal chemotherapy in patients with newly diagnosed …
Leptomeningeal metastases: results of different therapeutic approaches
M De Wit, V Lange-Brock, A Kruell… - Journal of Clinical …, 2007 - ascopubs.org
2047 Background: The aim of this study was to compare different treatment options for
patients with leptomeningeal metastases (LM). Method: In this retrospective single center …
patients with leptomeningeal metastases (LM). Method: In this retrospective single center …