Introduction Metastatic breast cancer (MBC) with leptomeningeal metastases (LM) has
dismal survival. We aim to determine if modern systemic therapy, especially the …

Leptomeningeal metastases (LM) in breast cancer patients are rare but often accompanied
by devastating neurological symptoms and carry a very poor prognosis, even if treated. To …

The study aimed to assess factors affecting survival of breast cancer patients suffering
leptomeningeal metastasis (LM) and to compare survivals in patients with LM as the first and …

Background: Survival of patients with leptomeningeal metastases (LM) and impaired
functional status is limited to several months, and rarely does neurological function improve …

Leptomeningeal metastases arise from cancer cell entry into the subarachnoid space,
inflicting significant neurologic morbidity and mortality across a wide range of malignancies …

Leptomeningeal metastasis (LM) is a debilitating complication that usually occurs late in the
course of metastatic disease in patients with solid tumours. Without treatment patients die …

Purpose Leptomeningeal disease (LMD) is a devastating complication of metastatic breast
cancer (MBC). It is critical to better understand the risk factors, natural history, and treatment …

Opinion statement Brain metastasis arising from breast cancer is associated with a poor
prognosis. Various systemic chemotherapy and targeted therapies which are effective …

The aim of the study was to define biological subtypes of breast cancer that have the
propensity to metastasize to the leptomeninges and to assess factors influencing survival …

Since most chemotherapy agents do not cross the blood brain barrier, the classical
approach for leptomeningeal metastasis (LM) of breast cancer is the administration of …