Preclinical studies of mesenchymal stem cell (MSC) administration in chronic obstructive pulmonary disease (COPD): a systematic review and meta-analysis

X Liu, Q Fang, H Kim - PloS one, 2016 - journals.plos.org
Background In the last two decades, mesenchymal stem cells (MSCs) have been pre-
clinically utilized in the treatment of a variety of kinds of diseases including chronic …

Mesenchymal stem cell administration in patients with chronic obstructive pulmonary disease: state of the science

SL Cheng, CH Lin, CL Yao - Stem Cells International, 2017 - Wiley Online Library
Patients with chronic obstructive pulmonary disease (COPD) have chronic, irreversible
airway inflammation; currently, there is no effective or curative treatment and the main goals …

Mesenchymal stromal cell therapy in COPD: from bench to bedside

MA Antunes, JR Lapa e Silva… - International Journal of …, 2017 - Taylor & Francis
COPD is the most frequent chronic respiratory disease and a leading cause of morbidity and
mortality. The major risk factor for COPD development is cigarette smoke, and the most …

A placebo-controlled, randomized trial of mesenchymal stem cells in COPD

DJ Weiss, R Casaburi, R Flannery, M LeRoux-Williams… - Chest, 2013 - Elsevier
Background COPD is a devastating disease affecting millions worldwide. As disease
pathogenesis includes both chronic pulmonary and systemic inflammation, antiinflammatory …

Stem cell therapy for COPD: hope and exploitation

MK Glassberg, I Csete, E Simonet, SJ Elliot - Chest, 2021 - Elsevier
COPD is a chronic inflammatory and destructive disease characterized by progressive
decline in lung function that can accelerate with aging. Preclinical studies suggest that …

Mesenchymal stem cell therapy for the treatment of chronic obstructive pulmonary disease

B D'Agostino, N Sullo, D Siniscalco… - Expert opinion on …, 2010 - Taylor & Francis
Recent studies have revealed that adult stem cells such as bone marrow-derived cells
contribute to lung tissue regeneration and protection, and thus administration of exogenous …

Biological effects and mechanisms of action of mesenchymal stem cell therapy in chronic obstructive pulmonary disease

Z Jin, X Pan, K Zhou, H Bi, L Wang… - Journal of …, 2015 - journals.sagepub.com
Chronic obstructive pulmonary disease (COPD) is the most frequent chronic respiratory
disease and a leading cause of morbidity and mortality, worldwide. Given that the foremost …

Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?

W Broekman, PPSJ Khedoe, K Schepers, H Roelofs… - Thorax, 2018 - thorax.bmj.com
COPD is characterised by tissue destruction and inflammation. Given the lack of curative
treatments and the progressive nature of the disease, new treatments for COPD are highly …

Stem cell therapy for chronic obstructive pulmonary disease

YT Chen, K Miao, L Zhou, WN Xiong - Chinese Medical Journal, 2021 - mednexus.org
Chronic obstructive pulmonary disease (COPD), characterized by persistent and not fully
reversible airflow restrictions, is currently one of the most widespread chronic lung diseases …

[HTML][HTML] Stem cell therapies for chronic obstructive pulmonary disease: current status of pre-clinical studies and clinical trials

Z Sun, F Li, X Zhou, KF Chung, W Wang… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is a respiratory disease that has a major
impact worldwide. The currently-available drugs mainly focus on relieving the symptoms of …