In pulmonary sarcoidosis, activated T cells accumulate in the lungs. We hypothesized that
the balance between the T-helper type 1 (Th1) cytokines (interferon [IFN]-γ and interleukin …

The pathogenesis of pulmonary sarcoidosis has been related to an increased production of
Th1-like cytokines. However, cytokine expression in sarcoidosis has not been systematically …

BACKGROUND Pulmonary sarcoidosis is characterised by a mononuclear alveolitis with a
predominance of CD4+ T cells and macrophages. We determined the intracellular …

Cytokines released by T lymphocytes activated in the course of sarcoidosis, eg, interleukin-2
(IL-2) and interferon-gamma (IFN-gamma), indicate the presence of Th1 cells leading to the …

We have characterized the activation state of T cells in the bronchoalveolar lavage fluid
(BALF) and peripheral blood (PB) from patients with sarcoidosis, to obtain more information …

BACKGROUND The granulomatous inflammation in sarcoidosis is driven by the interplay
between T cells and macrophages. To gain a better understanding of this process the …

BACKGROUND: Sarcoidosis is a systemic granulomatous disorder of unknown origin
characterised by accumulation of T lymphocytes and macrophages in multiple organs …

Background: Sarcoidosis is thought to be a type-1 cytokine-mediated disorder. However, few
data are available on the profiles of cytokine expression by TH cells at the single-cell level …

Darlington P, Haugom‐Olsen H, von Sivers K, Wahlström J, Runold M, Svjatoha V, Porwit A,
Eklund A, Grunewald J (Karolinska Institutet, Stockholm, Sweden). T‐cell phenotypes in …

We investigated surface antigens and spontaneous cytokine production of T cells from
broncho-alveolar lavage fluid (BALF) and aqueous humor (AH) from pulmonary sarcoidosis …