Identification of glycerophospholipids using self-built recognition software based on positive and negative ion high-resolution mass spectrometric fragmentation …

Y Zhao, X Zhao, T Li, X Wang, C Zhong, X Wang, P Li - Talanta, 2022 - Elsevier
Glycerophospholipids (GPs) have a wide variety and complex structure, which makes their
identification challenging. Our software affords a novel tool for the automated identification of …

Lipidomic Analysis of Glycerophospholipid Molecular Species in Biological Samples

X Han - Mass Spectrometry for Lipidomics: Methods and …, 2023 - Wiley Online Library
In the chapter, analysis of cellular glycerophospholipid (GPL) molecular species based on
the strategy of pattern recognition is described. The molecular mechanisms underpinning …

Lyso‐form fragment ions facilitate the determination of stereospecificity of diacyl glycerophospholipids

W Hou, H Zhou, MB Khalil, D Seebun… - Rapid …, 2011 - Wiley Online Library
In this work we report the development of a novel methodology for the determination of
stereospecificity of diacyl glycerophospholipids, including glycerophosphatidic acids (PA) …

Localization of cyclopropyl groups and alkenes within glycerophospholipids using gas‐phase ion/ion chemistry

DSM Shenault, SA McLuckey… - Journal of Mass …, 2023 - Wiley Online Library
Shotgun lipid analysis using electrospray ionization tandem mass spectrometry (ESI‐
MS/MS) is a common approach for the identification and characterization of …

Glycerophospholipid profiling by high‐performance liquid chromatography/mass spectrometry using exact mass measurements and multi‐stage mass spectrometric …

EM Hein, LM Blank, J Heyland… - … Journal Devoted to …, 2009 - Wiley Online Library
A profiling method for glycerophospholipids (GPs) in biological samples was developed
using reversed‐phase high‐performance liquid chromatography (RP‐HPLC) coupled to …

Coupling headgroup and alkene specific solution modifications with gas-phase ion/ion reactions for sensitive glycerophospholipid identification and characterization

ET Franklin, SWJ Shields, JM Manthorpe… - Journal of the …, 2020 - ACS Publications
Shotgun lipidomics provides sensitive and fast lipid identification without the need for
chromatographic separation. Challenges faced by shotgun analysis of glycerophospholipids …

[PDF][PDF] Characterization of Molecular Glycerophospholipids by Quadrupole Time-of-Flight Mass Spectrometry

K Ekroos - 2003 - researchgate.net
The physical properties of glycerophospholipids (GPLs) are not only determined by the head
group (HG), but also by their fatty acid (FA) chains, which affect their distribution and function …

Automated identification and quantification of glycerophospholipid molecular species by multiple precursor ion scanning

CS Ejsing, E Duchoslav, J Sampaio, K Simons… - Analytical …, 2006 - ACS Publications
We report a method for the identification and quantification of glycerophospholipid molecular
species that is based on the simultaneous automated acquisition and processing of 41 …

Toward complete structure elucidation of glycerophospholipids in the gas phase through charge inversion ion/ion chemistry

CE Randolph, SJ Blanksby, SA McLuckey - Analytical chemistry, 2019 - ACS Publications
Shotgun lipidomics has recently gained popularity for lipid analysis. Conventionally, shotgun
analysis of glycerophospholipids via direct electrospray ionization tandem mass …

A rapid ambient ionization-mass spectrometry approach to monitoring the relative abundance of isomeric glycerophospholipids

RL Kozlowski, TW Mitchell, SJ Blanksby - Scientific reports, 2015 - nature.com
Glycerophospholipids with two, non-equivalent fatty acyl chains can adopt one of two
isomeric forms depending on the relative position of substitutions on the glycerol backbone …