Curcumin: a dietary phytochemical for targeting the phenotype and function of dendritic cells

K Rahimi, K Hassanzadeh… - Current medicinal …, 2021 - ingentaconnect.com
Dendritic cells (DCs) are the most powerful antigen-presenting cells which link the innate
and adaptive immune responses. Depending on the context, DCs initiate the immune …

Curcumin prevents human dendritic cell response to immune stimulants

SA Shirley, AJ Montpetit, RF Lockey… - … and biophysical research …, 2008 - Elsevier
Curcumin, a compound found in the Indian spice turmeric, has anti-inflammatory and
immunomodulatory properties, though the mechanism remains unclear. Dendritic cells …

Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-κB as potential targets

GY Kim, KH Kim, SH Lee, MS Yoon, HJ Lee… - The Journal of …, 2005 - journals.aai.org
Curcumin has been shown to exhibit anti-inflammatory, antimutagenic, and anticarcinogenic
activities. However, the effect of curcumin on the maturation and immunostimulatory function …

Curcumin induces maturation-arrested dendritic cells that expand regulatory T cells in vitro and in vivo

NM Rogers, S Kireta, PTH Coates - Clinical & Experimental …, 2010 - academic.oup.com
Dendritic cells (DC) and regulatory T cells (Tregs) are vital to the development of transplant
tolerance. Curcumin is a novel biological agent extracted from Curcuma longa (turmeric) …

Therapeutic effects of curcumin in inflammatory and immune‐mediated diseases: A nature‐made jack‐of‐all‐trades?

E Abdollahi, AA Momtazi, TP Johnston… - Journal of cellular …, 2018 - Wiley Online Library
Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities.
Novel animal and human studies indicate that curcumin can affect different immune cells …

Immunomodulatory and therapeutic activity of curcumin

RM Srivastava, S Singh, SK Dubey, K Misra… - International …, 2011 - Elsevier
Inflammation is a disease of vigorous uncontrolled activated immune responses.
Overwhelming reports have suggested that the modulation of immune responses by …

Multifaceted roles of curcumin: two sides of a coin!

SA Marathe, I Dasgupta, DP Gnanadhas… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Curcumin has been a front-line topic of mainstream scientific research for a
variety of diseases from cancer to Alzheimer's to infectious diseases. Curcumin suppresses …

Curcumin Inhibits CD4+ T Cell Activation, but Augments CD69 Expression and TGF-β1-Mediated Generation of Regulatory T Cells at Late Phase

G Kim, MS Jang, YM Son, MJ Seo, SY Ji, SH Han… - PLoS …, 2013 - journals.plos.org
Background Curcumin is a promising candidate for a natural medicinal agent to treat chronic
inflammatory diseases. Although CD4+ T cells have been implicated in the pathogenesis of …

Curcumin: powerful immunomodulator from turmeric

DR Cundell, F Wilkinson - Current Immunology Reviews, 2014 - ingentaconnect.com
Curcumin is the phytochemical derived from the bulb of the plant Curcuma longa and is the
major component of turmeric. The herb has been used for thousands of years, initially to …

Curcumin as a natural modulator of B lymphocytes: evidence from in vitro and in vivo studies

A Mohammadi, K Mashayekhi… - Mini reviews in …, 2022 - ingentaconnect.com
B cells are the only player of humoral immune responses by the production of various types
of antibodies. However, B cells are also involved in the pathogenesis of several immune …