Is translocation (8; 21) a" favorable" cytogenetic rearrangement in acute myeloid leukemia?

P Fenaux, JL Lai, C Preudhomme, JP Jouet… - … revue française d' …, 1990 - europepmc.org
Twenty-three patients with de novo acute myeloid leukemia (AML) and t (8; 21)(q22; q22),
including 2 children aged 7 and 14 and 21 adults aged 16 to 68 (median 29), were treated …

Clinical heterogeneity in acute myelogenous leukemia with the 8; 21 translocation

M Hagihara, H Kobayashi, H Miyachi… - The Keio journal of …, 1991 - jstage.jst.go.jp
Nine acute myelogenous leukemia (AML) patients with a translocation 8; 21, who were
treated at Keio University Hospital between 1983 and August 1990, were reviewed. All of …

A white blood cell index as the main prognostic factor in t (8; 21) acute myeloid leukemia (AML): a survey of 161 cases from the French AML Intergroup

S Nguyen, T Leblanc, P Fenaux, F Witz… - Blood, The Journal …, 2002 - ashpublications.org
While the t (8; 21) translocation is one of the most recurrent chromosomal abnormalities in
acute myeloid leukemia, prognostic studies have been hampered by the relatively few …

Translocation t (9; 11)(p21; q23) in pediatric de novo and secondary acute myeloblastic leukemia.

C Sandoval, DR Head, J Mirro Jr, FG Behm, GD Ayers… - Leukemia, 1992 - europepmc.org
The t (9; 11)(p21; q23) has been associated with characteristic clinical features and a
superior treatment outcome in previously untreated pediatric acute myeloblastic leukemia …

Adult patients with de novo acute myeloid leukemia and t (9; 11)(p22; q23) have a superior outcome to patients with other translocations involving band 11q23: a …

K Mrózek, K Heinonen, D Lawrence… - Blood, The Journal …, 1997 - ashpublications.org
Following reports of childhood acute myeloid leukemia (AML) showing that patients with t (9;
11)(p22; q23) have a better prognosis than those with translocations between 11q23 and …

Prognostic implications of t (10; 11) translocations in childhood acute myelogenous leukemia: a report from the Children's Cancer Group

JN Casillas, WG Woods, SP Hunger… - Journal of pediatric …, 2003 - journals.lww.com
Purpose: This was a retrospective analysis of outcome based on cytogenetics for a
Children's Cancer Group phase 3 trial of acute myelogenous leukemia (AML)(CCG-2891) …

Acute myelogenous leukemia with an 8; 21 translocation: a report on 148 cases from the Groupe Français de Cytogénétique Hématologique

GF de Cytogenetique Hematologique - Cancer Genetics and cytogenetics, 1990 - Elsevier
A retrospective study of 148 previously untreated patients with acute nonlymphocytic
leukemia (ANLL) presenting at (8; 21) was undertaken by the Groupe Français de …

Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: a report on 283 cases

P Fenaux, C Preudhomme, JL Lai… - British Journal of …, 1989 - Wiley Online Library
Cytogenetic analysis was successfully performed at diagnosis in 283 patients with de novo
acute myeloid leukaemia (AML), including eight children aged 6–15 and 275 adults. Mean …

Fifty-one patients with acute myeloid leukemia and translocation t (8; 21)(q22; q22): an additional deletion in 9q is an adverse prognostic factor.

C Schoch, D Haase, T Haferlach, H Gudat, T Büchner… - Leukemia, 1996 - europepmc.org
The translocation t (8; 21)(q22; q22) occurs in 6 to 12 percent of patients with AML, and
usually predicts a good response to chemotherapy with a high remission rate and a …

Acute myeloid leukemia with translocation (8; 21). Cytomorphology, dysplasia and prognostic factors in 41 cases

T Haferlach, JM Bennett, H LÖFfler… - Leukemia & …, 1996 - Taylor & Francis
The translocation t (8; 21) is one of the most common structural aberrations in acute myeloid
leukemia (AML). Excellent response rates and a better relapse-free survival have been …