Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …

The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …

Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

In addition to their role in generating energy (ATP), other possible regulatory functions for
mitochondria in the mature oocyte, preimplantation stage embryo and differentiating …

The role of mitochondria as central determinants of development competence of oocytes
and preimplantation stage embryos is considered in the context of the diverse activities …

Mitochondria, originally of bacterial origin, are highly dynamic organelles that have evolved
a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage …

Mitochondria are maternally inherited, semi-autonomous organelles with their own genomes
(mtDNA), largely responsible for the generation of energy in the form of cellular ATP …

BACKGROUND: The magnitude of the inner mitochondrial membrane potential (ΔΨm)
appears to influence the level of certain mitochondrial activities including regulation of ionic …

The oocyte requires a vast supply of energy after fertilization to support critical events such
as spindle formation, chromatid separation, and cell division. Until blastocyst implantation …

Mitochondria are highly dynamic organelles and their distribution, structure and activity
affect a wide range of cellular functions. Mitochondrial membrane potential (∆ Ψm) is an …