At fertilisation, Ca2+ signals activate embryonic development by stimulating metabolism,
exocytosis and endocytosis, cytoskeletal remodelling, meiotic resumption and recruitment of …

Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …

The aim of this study has been to observe, by electron microscopy, the morphological
changes affecting mitochondria and associated organelles in the human female germ cell …

To clarify the relationship between mitochondria and embryo development, we collected
human unfertilized oocytes, early embryos, and arrested embryos. Unfertilized oocytes and …

The relationship between the ATP content of mature human oocytes and developmental
potential after uterine transfer of sibling embryos was examined in 20 non-male factor in …

Mitochondria (mt) have been reported to be closely related to the maturation of mammalian
oocytes, but their function in oocyte maturation has not been elucidated. In this study, we …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

The role of mitochondrial metabolism in the development of preimplantation embryos is
unclear. To clarify the importance of mitochondria in early development, the fluorescent …

The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

STUDY QUESTION Does the oxygen concentration in the culture medium [either physiologic
(5%) or atmospheric (20%)] affect mitochondrial ultrastructure and function in …