Augmentative effect of Nocardia rubra cell-wall skeleton (N-CWS) on lymphokine-activated killer (LAK) cell induction

S Yokota, T Shirasaka, H Nishikawa, S Hosoe… - Cancer Immunology …, 1988 - Springer
The present study elucidated that N-CWS augments the cytolytic activity against 3LL tumor
cells of LAK cells from N-CWS-immunized mice administered ip with rIL-2. This …

Augmentative effect ofNocardia rubra cell-wall skeleton on the induction of human lymphokine-activated killer (LAK) cells by the production of LAK cell helper factor(s)

T Shirasaka, I Kawase, M Okada, M Kitahara… - Cancer Immunology …, 1989 - Springer
Nocardia rubra cell wall skeleton (N-CWS) was found to synergistically augment lymphokine-
activated killer (LAK) cell generation from human peripheral blood mononuclear cells …

Synergistic Effect of Nocardia rubra Cell Wall Skeleton and Recombinant Interleukin 2 for in Vivo Induction of Lymphokine-activated Killer Cells

K Miyazaki, K Yasumoto, T Yano, G Matsuzaki… - Cancer research, 1991 - AACR
C57BL/6 mice inoculated ip with 3LL tumor cells were treated by local combination therapy
with Nocardia rubra cell wall skeleton (N-CWS) and recombinant interleukin 2 (rIL-2). The …

[PDF][PDF] Enhancing natural killer cell-mediated cancer immunotherapy by the biological macromolecule nocardia rubra cell-wall skeleton

J Wu, B He, M Miao, X Han, H Dai, H Dou… - Pathology and …, 2022 - por-journal.com
The biological macromolecule Nocardia rubra cell-wall skeleton (Nr-CWS) has
wellestablished immune-stimulating and anti-tumor activities. However, the role of Nr-CWS …

The biological macromolecule Nocardia rubra cell‐wall skeleton as an avenue for cell‐based immunotherapy

Y Meng, J Sun, X Wang, Y Ma, C Kong… - Journal of Cellular …, 2019 - Wiley Online Library
Promoting the antitumor effects of cell‐based immunotherapy for clinical application remains
a difficult challenge. Nocardia rubra cell‐wall skeleton (N‐CWS) is an immunotherapeutic …

A functional and phenotypic comparison of murine natural killer (NK) cells and lymphokine‐activated killer (LAK) cells

DW Hoskin, J Stankova, SK Anderson… - International journal of …, 1989 - Wiley Online Library
Lymphokine‐activated killer (LAK) cells have been defined as interleukin 2 (lL‐2)‐activated
cytolytic effector cells exhibiting non‐MHC restricted killing against a wide range of NK …

Lymphokine-activated killer cells in rats: analysis of progenitor and effector cell phenotype and relationship to natural killer cells

NL Vujanovic, RB Herberman, MW Olszowy… - Cancer research, 1988 - AACR
The progenitor and effector cell phenotype of lymphokine-activated killer (LAK) cells
generated in F344 rats by recombinant human interleukin 2 (IL-2)(rIL-2) were analyzed …

Natural killer cell activity in reticulum‐cell sarcomas of SJL/J MICE. III. Characterization of the effector cells within RCS that mediate NK lysis

KL Fitzgerald, JS McMaster… - International Journal of …, 1981 - Wiley Online Library
Various cell depletion techniques were employed to identify the cells responsible for the
natural killer (NK) activity against YAC‐1 targets that is present in lymphoid tissues of SJL/J …

Preparation of NK-enriched LAK cells--their potential cytotoxic and ADCC activities

Y Kobayashi, T Sudo, N Matsushita… - Gan to Kagaku ryoho …, 2003 - europepmc.org
We examined several culture methods to induce proliferation of natural killer (NK) cells from
peripheral blood mononuclear cells (PBMC). In the presence of IL-2, a remarkable …

[引用][C] Identification of a recognition structure on rat natural killer cells

DL Evans, DT Harris, HS Koren… - Natural Killer Cells …, 1990 - karger.com
Results Inhibition of NK Cell Cytotoxicity. To determine the effects of mAb treatment on both
in vivo and in vitro derived NK cells, the cytotoxicity of F344 unfractionated and nylon wool …