[HTML][HTML] The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and …
M van Keimpema, LJ Grüneberg, EJM Schilder-Tol… - …, 2017 - ncbi.nlm.nih.gov
The forkhead transcription factor FOXP1 is generally regarded as an oncogene in activated
B cell-like diffuse large B-cell lymphoma. Previous studies have suggested that a small …
B cell-like diffuse large B-cell lymphoma. Previous studies have suggested that a small …
[HTML][HTML] N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells
PJ Brown, DM Gascoyne, L Lyne, H Spearman… - …, 2016 - ncbi.nlm.nih.gov
Strong FOXP1 protein expression is a poor risk factor in diffuse large B-cell lymphoma and
has been linked to an activated B-cell-like subtype, which preferentially expresses short …
has been linked to an activated B-cell-like subtype, which preferentially expresses short …
Potentially oncogenic B-cell activation–induced smaller isoforms of FOXP1 are highly expressed in the activated B cell–like subtype of DLBCL
PJ Brown, SL Ashe, E Leich, C Burek… - Blood, The Journal …, 2008 - ashpublications.org
The FOXP1 forkhead transcription factor is targeted by recurrent chromosome translocations
in several subtypes of B-cell non-Hodgkin lymphomas, where high-level FOXP1 protein …
in several subtypes of B-cell non-Hodgkin lymphomas, where high-level FOXP1 protein …
The significance of FOXP1 in diffuse large B-cell lymphoma
DM Gascoyne, AH Banham - Leukemia & lymphoma, 2017 - Taylor & Francis
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of mature B-cell
lymphoma. While the majority of patients are cured with immunochemotherapy incorporating …
lymphoma. While the majority of patients are cured with immunochemotherapy incorporating …
[HTML][HTML] Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma
S Uddin, AR Hussain, M Ahmed, K Siddiqui… - …, 2012 - ncbi.nlm.nih.gov
Background FoxM1 has been shown to play a critical role in the pathogenesis of various
epithelial malignancies. However, its role in lymphoid malignancies has not been fully …
epithelial malignancies. However, its role in lymphoid malignancies has not been fully …
[HTML][HTML] Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1
L Rouhigharabaei, J Finalet Ferreiro, T Tousseyn… - PLoS …, 2014 - journals.plos.org
The transcription factor FOXP1 is implicated in the pathogenesis of B-cell lymphomas
through chromosomal translocations involving either immunoglobulin heavy chain (IGH) …
through chromosomal translocations involving either immunoglobulin heavy chain (IGH) …
FOXP1 expression and its clinicopathologic significance in nodal and extranodal diffuse large B-cell lymphoma
BH Yu, XY Zhou, BZ Li, XY Xiao, SY Yan, DR Shi - Annals of Hematology, 2011 - Springer
The aims of this study were to investigate FOXP1 expression in nodal and extranodal diffuse
large B-cell lymphoma (DLBCL) and its association with the subclassification and other …
large B-cell lymphoma (DLBCL) and its association with the subclassification and other …
Strong expression of FOXP1 identifies a distinct subset of diffuse large B-cell lymphoma (DLBCL) patients with poor outcome
SL Barrans, JAL Fenton, A Banham, RG Owen… - Blood, 2004 - ashpublications.org
Abstract FOXP1 (Forkhead box-P1) is a winged-helix transcription factor that is differentially
expressed in resting and activated B cells. FOXP1 expression has been demonstrated in a …
expressed in resting and activated B cells. FOXP1 expression has been demonstrated in a …
Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma
AH Banham, JM Connors, PJ Brown, JL Cordell… - Clinical cancer …, 2005 - AACR
Gene expression profiling studies have reported up-regulated mRNA expression of the
FOXP1 forkhead transcription factor in response to normal B-cell activation and high …
FOXP1 forkhead transcription factor in response to normal B-cell activation and high …
[HTML][HTML] FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures
KK Wong, DM Gascoyne, EJ Soilleux, L Lyne… - Oncotarget, 2016 - ncbi.nlm.nih.gov
FOXP2 shares partially overlapping normal tissue expression and functionality with FOXP1;
an established diffuse large B-cell lymphoma (DLBCL) oncogene and marker of poor …
an established diffuse large B-cell lymphoma (DLBCL) oncogene and marker of poor …