Biological functions of tear film

SC Pflugfelder, ME Stern - Experimental eye research, 2020 - Elsevier
Tears have a vital function to protect and lubricate the ocular surface. Tear production,
distribution and clearance is tightly regulated by the lacrimal functional unit (LFU) to meet …

The ocular surface and tear film and their dysfunction in dry eye disease

M Rolando, M Zierhut - Survey of ophthalmology, 2001 - Elsevier
The ocular surface, tear film, lacrimal glands, and eyelids act as a functional unit to preserve
the quality of the refractive surface of the eye and to resist injury and protect the eye against …

[HTML][HTML] Complexity of the tear film: importance in homeostasis and dysfunction during disease

DA Dartt, MDP Willcox - Experimental eye research, 2013 - ncbi.nlm.nih.gov
The tear film is a unique thin fluid layer of approximately 3μm thick and 3μl in volume that
covers the outer mucosal surfaces of the eye. As such it is the interface of the ocular surface …

Regulation of tear secretion

DA Dartt - Lacrimal gland, tear film, and dry eye syndromes: basic …, 1994 - Springer
The tear film, which is the interface between the external environment and the ocular surface
has several differing functions. 1 It forms a smooth refracting surface over the otherwise …

Analysis and function of the human tear proteins

A Kijlstra, A Kuizenga - Lacrimal gland, tear film, and dry eye syndromes …, 1994 - Springer
The ocular mucosa contains various proteins exerting numerous functions including
amongst others: anti-microbial defense, lubrication, wound healing and regulation of the …

Tear film mucins: front line defenders of the ocular surface; comparison with airway and gastrointestinal tract mucins

RR Hodges, DA Dartt - Experimental eye research, 2013 - Elsevier
The ocular surface including the cornea and conjunctiva and its overlying tear film are the
first tissues of the eye to interact with the external environment. The tear film is complex …

Cellular origin of mucins of the ocular surface tear film

IK Gipson, T Inatomi - Lacrimal Gland, Tear Film, and Dry Eye Syndromes …, 1998 - Springer
The surface of the eye is covered by a tear film that has been estimated to be 40 μm thick.
1.2 The film is extraordinarily regular over the cornea where it is the primary refractive …

TFOS DEWS II tear film report

MDP Willcox, P Argüeso, GA Georgiev, JM Holopainen… - The ocular …, 2017 - Elsevier
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Towards a closed eye model of the pre-ocular tear layer

RA Sack, A Beaton, S Sathe, C Morris, M Willcox… - Progress in retinal and …, 2000 - Elsevier
Although the tear film has been extensively studied as it exists in the open eye state, until
recently very little was known as to what happens to the tear film on eye closure. Recent …

The lacrimal gland and its role in dry eye

CD Conrady, ZP Joos, BCK Patel - Journal of ophthalmology, 2016 - Wiley Online Library
The human tear film is a 3‐layered coating of the surface of the eye and a loss, or reduction,
in any layer of this film may result in a syndrome of blurry vision and burning pain of the eyes …