Gas chromatography–mass spectrometry (GC–MS) has been widely used in metabonomics
analyses of biofluid samples. Biofluids provide a wealth of information about the metabolism …

To maximize the utility of gas chromatography–mass spectrometry (GC-MS) in
metabonomics research, all stages of the experimental design should be standardized …

Metabolomics, one of the 'omic'sciences in systems biology, is the global assessment and
validation of endogenous small-molecule metabolites within a biologic system. Analysis of …

MS and HPLC are commonly used for compound characterization and obtaining structural
information; in the field of metabonomics, these two analytical techniques are often …

One of the objectives of metabonomics is to identify subtle changes in metabolite profiles
between biological systems of different physiological or pathological states. Gas …

Metabolome analyses of body fluids are challenging due pre-analytical variations, such as
pre-processing delay and temperature, and constant dynamical changes of biochemical …

Metabolomics is the field of omics research that offers valuable insights into the complex
composition of biological samples. It has found wide application in clinical diagnostics …

For decades gas chromatography has been and will remain an irreplaceable analytical
technique in many research areas for both quantitative analysis and qualitative …

Sample preparation plays a critical role in untargeted profiling of biological fluids and tissues
by nuclear magnetic resonance and mass spectrometry for biomarker discovery. In this …

The widespread availability, suitability, and high sensitivity of chromatography-mass
spectrometry for chemical profiling analysis of multi-component biosamples are …