Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease

SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …

COVID-19 mortality as a fingerprint of biological age

MC Polidori, H Sies, L Ferrucci, T Benzing - Ageing research reviews, 2021 - Elsevier
Abstract Corona virus disease 2019 (COVID-19) is a global emergency able to overwhelm
the healthcare capacities worldwide and to affect the older generation especially. When …

Geriatric syndromes and SARS-Cov-2: more than just being old

I Aprahamian, M Cesari - The Journal of frailty & aging, 2020 - Springer
128 biological background (eg, the so-called phenomenon of inflamm-aging); all aspects
that can complicate the course of disease, much more than the mere number of years lived …

Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

GH Meftahi, Z Jangravi, H Sahraei, Z Bahari - Inflammation Research, 2020 - Springer
Abstract Purpose Novel Coronavirus disease 2019 (COVID-19), is an acute respiratory
distress syndrome (ARDS), which is emerged in Wuhan, and recently become worldwide …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

Geriatric population during the COVID-19 pandemic: problems, considerations, exigencies, and beyond

K Dhama, SK Patel, R Kumar, J Rana… - Frontiers in public …, 2020 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more
than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020 …

Immunesenescence: a predisposing risk factor for the development of COVID-19?

J Hazeldine, JM Lord - Frontiers in immunology, 2020 - frontiersin.org
Bearing a strong resemblance to the phenotypic and functional remodeling of the immune
system that occurs during aging (termed immunesenescence), the immune response to …

Long-term effects of malnutrition on severity of COVID-19

A Kurtz, K Grant, R Marano, A Arrieta, K Grant Jr… - Scientific Reports, 2021 - nature.com
The COVID-19 pandemic is a public health crisis that has the potential to exacerbate
worldwide malnutrition. This study examines whether patients with a history of malnutrition …

[HTML][HTML] Malnutrition and sarcopenia in COVID-19 survivors

S Grund, JM Bauer - Clinics in Geriatric Medicine, 2022 - ncbi.nlm.nih.gov
The observation that nutritional status and functionality are deeply intertwined in older
persons holds especially true in the context of the COVID-19 pandemic. One of the key …