In hereditary MTC recommended age surgery in carriers of the mutation depends on its
localization in the gene RET, which determines the probable age of tumor onset …

Medullary thyroid cancer (MTC) is a neuroendocrine malignancy, which originates from C
cells (parafollicular) of the gland. MTC is inherited in autosomal dominant pattern in 20–25 …

In this paper we have briefly outlined our views on the management of hereditary MTC. We
have stressed the fact that although many patients with the usual form of disease have an …

Background Twenty-five percent of medullary thyroid cancer (MTC) cases are hereditary.
The ideal age for prophylactic thyroidectomy is based on the specific RET mutation involved …

Although the onset of hereditary medullary thyroid cancer (MTC) depends on mutational risk,
the impact of that risk on lymph node metastasis is unclear. Included in this investigation …

Hereditary medullary thyroid carcinoma (hereditary MTC) is a rare malignancy, accounting
for 25–30% of all MTC. It occurs as part of multiple endocrine neoplasia type 2 (MEN 2) …

Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy. About 75% are sporadic
(sMTC) while the remaining 25% are hereditary (hMTC). The treatment of choice for both …

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor originating from the
thyroid C cells producing mainly calcitonin (CTN) used as tumor marker. MTC occurs either …

Objective In children with RET proto-oncogene mutation, curative treatment of medullary
thyroid carcinoma (MTC) is possible by prophylactic thyroidectomy. Recommendations on …

Introduction Long-term outcomes after curative resection in patients with germline RET
mutations and medullary thyroid cancer (MTC) are highly variable and mutation-specific …