Role of liver sinusoidal endothelial cells in liver diseases

J Gracia-Sancho, E Caparrós… - Nature reviews …, 2021 - nature.com
Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Liver sinusoidal endothelial cells: Physiology and role in liver diseases

J Poisson, S Lemoinne, C Boulanger, F Durand… - Journal of …, 2017 - Elsevier
Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells
representing the interface between blood cells on the one side and hepatocytes and hepatic …

Liver sinusoidal endothelial cells—gatekeepers of hepatic immunity

S Shetty, PF Lalor, DH Adams - Nature reviews Gastroenterology & …, 2018 - nature.com
Liver sinusoidal endothelial cells (LSECs) line the low shear, sinusoidal capillary channels
of the liver and are the most abundant non-parenchymal hepatic cell population. LSECs do …

The evolving role of liver sinusoidal endothelial cells in liver health and disease

MJ McConnell, E Kostallari, SH Ibrahim, Y Iwakiri - Hepatology, 2023 - journals.lww.com
LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …

[HTML][HTML] Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo

PF Lalor, WK Lai, SM Curbishley, S Shetty… - World journal of …, 2006 - ncbi.nlm.nih.gov
The hepatic sinusoids are lined by a unique population of hepatic sinusoidal endothelial
cells (HSEC), which is one of the first hepatic cell populations to come into contact with …

The role of sinusoidal endothelial cells in the axis of inflammation and cancer within the liver

AL Wilkinson, M Qurashi, S Shetty - Frontiers in physiology, 2020 - frontiersin.org
Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

Prominent receptors of liver sinusoidal endothelial cells in liver homeostasis and disease

E Pandey, AS Nour, EN Harris - Frontiers in physiology, 2020 - frontiersin.org
Liver sinusoidal endothelial cells (LSECs) are the most abundant non-parenchymal cells
lining the sinusoidal capillaries of the hepatic system. LSECs are characterized with …

Liver sinusoidal endothelial cells

KK Sørensen, J Simon‐Santamaria… - Comprehensive …, 2011 - Wiley Online Library
The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic
sinusoid and functions as a control post regulating and surveying the trafficking of molecules …

Liver sinusoidal endothelial cell: an update

LD DeLeve, AC Maretti-Mira - Seminars in liver disease, 2017 - thieme-connect.com
This update focuses on two main topics. First, recent developments in our understanding of
liver sinusoidal endothelial cell (LSEC) function will be reviewed, specifically elimination of …

Physiological role of sinusoidal endothelial cells and Kupffer cells and their implication in the pathogenesis of liver injury

S Arii, M Imamura - Journal of Hepato-Biliary-Pancreatic Surgery, 2000 - Springer
We reviewed the morphological characteristics and physiological functions of hepatic
sinusoidal endothelial cells (SECs) and Kupffer cells (KCs), both of which are major …