Aims Traditional serrated adenoma (TSA) is the least common subtype of serrated colorectal
polyp. Large protuberant lesions are easily recognised; however, the origins of TSAs are not …

Until the past two decades, almost all colorectal polyps were divided into two main groups:
hyperplastic polyps and adenomas. Sessile serrated adenomas presented endoscopic …

Serrated polyps have long been thought to lack malignant potential in the human
colorectum. However, identification of the serrated pathway to colorectal cancer based on …

Bowel cancer screening programmes have highlighted to endoscopists and clinicians the
spectrum of serrated colorectal lesions. One of the most significant developments has been …

The differential diagnosis of rectal serrated polyps is challenging due to its unique anatomic
location, the evolving concept of serrated polyps over the past several years, and to …

Serrated polyps are important contributors to the burden of colorectal cancers (CRC). These
lesions were once considered to have no malignant potential, but currently up to 30% of all …

Sessile serrated adenoma/polyps (SSA/Ps) are early precursor lesions in the serrated
neoplasia pathway, which results in colorectal carcinomas with BRAF mutations, methylation …

More than 40 years ago Morson (1962) coined the paradigm that adenomas are the main
precursors of colorectal carcinoma (CRC) whereas hyperplastic polyps are" non-neoplastic" …

Objectives: To investigate the clinicopathologic and endoscopic features of precursor
lesions associated with traditional serrated adenomas (TSAs). Methods: Mutation studies for …

Context Sessile serrated adenomas/polyps (SSA/Ps) have been increasingly studied during
the last 10 years. However, their detailed anatomic distribution pattern has not been studied …