Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma

M Bettington, N Walker, C Rosty, I Brown, A Clouston… - Gut, 2017 - gut.bmj.com
Objective Sessile serrated adenomas (SSAs) are the precursors of at least 15% of colorectal
carcinomas, but their biology is incompletely understood. We performed a …

The cutting edge of serrated polyps: a practical guide to approaching and managing serrated colon polyps

BN Limketkai, D Lam-Himlin, MA Arnold… - Gastrointestinal …, 2013 - giejournal.org
The most common colonic polyps include the conventional adenomas (tubular,
tubulovillous, and villous adenomas) and serrated polyps. Serrated polyps account for as …

Serrated polyps: critical precursors to colorectal cancer

S Sweetser, TC Smyrk, A Sugumar - Expert Review of …, 2011 - Taylor & Francis
Colorectal polyps have been traditionally classified as either hyperplastic or adenomatous,
with only the latter progressing to carcinoma. However, it is now recognized that certain …

[HTML][HTML] Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E

I Mesteri, G Bayer, J Meyer, D Capper… - Modern Pathology, 2014 - Elsevier
Abstract BRAF V600E mutation in serrated lesions of the colon has been implicated as an
important mutation and as a specific marker for the serrated carcinogenic pathway. Recent …

Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types

S Oka, S Tanaka, T Hiyama, M Ito, Y Kitadai… - Gastrointestinal …, 2004 - Elsevier
BACKGROUND: Serrated adenoma is a distinct histologic colorectal lesion. There are two
macroscopic types: polypoid and superficial. The aim of this study was to clarify …

Sessile serrated adenoma: challenging discrimination from other serrated colonic polyps

AB Farris, J Misdraji, A Srivastava… - The American journal …, 2008 - journals.lww.com
Sessile serrated adenoma (SSA) is the proposed precursor for microsatellite unstable
colorectal carcinomas and some authorities recommend that SSAs should be managed …

Serrated neoplasia in the colorectum: gut microbiota and molecular pathways

X Kang, R Zhang, TN Kwong, RN Lui, WK Wu… - Gut …, 2021 - Taylor & Francis
Colorectal cancer (CRC) is a heterogeneous disease with different gene expression
patterns. There are two major colorectal carcinogenesis pathways: conventional adenoma …

Endoscopic characterization of sessile serrated adenomas/polyps with and without dysplasia

MWE Bouwens, YJ van Herwaarden, B Winkens… - …, 2014 - thieme-connect.com
Background and study aims: Sessile serrated adenomas/polyps (SSA/Ps) are precursors of
colorectal cancer (CRC), but their endoscopic detection can be difficult. We therefore …

Sessile serrated adenoma: a brief history and current status

EE Torlakovic, DC Snover - Critical Reviews™ in Oncogenesis, 2006 - dl.begellhouse.com
Sessile serrated adenoma (SSA) is a polyp of the large intestine, which was first described
in 1996. It presents as a solitary lesion or in a setting of a polyposis previously coined as" …

[HTML][HTML] Progressive methylation during the serrated neoplasia pathway of the colorectum

SM Dong, EJ Lee, ES Jeon, CK Park, KM Kim - Modern Pathology, 2005 - Elsevier
Serrated adenoma is a recently described entity characterized by having combined
architectural features of hyperplastic polyps and classical adenoma. To understand the role …