The combination of functional and structural MRI is a potential screening tool in Alzheimer's disease

CC Huang, WM Huang, CH Chen, ZY Jhou… - Frontiers in Aging …, 2018 - frontiersin.org
Introduction: This study aimed to survey the discrimination power of parameters from
cerebrospinal fluid (CSF) biomarkers, fluorodeoxyglucose uptake on PET (FDG-PET) …

Multimodal discrimination between normal aging, mild cognitive impairment and Alzheimer's disease and prediction of cognitive decline

CM Bauer, HJ Cabral, RJ Killiany - Diagnostics, 2018 - mdpi.com
Alzheimer's Disease (AD) and mild cognitive impairment (MCI) are associated with
widespread changes in brain structure and function, as indicated by magnetic resonance …

[HTML][HTML] Association between composite scores of domain-specific cognitive functions and regional patterns of atrophy and functional connectivity in the Alzheimer's …

CO Amaefule, M Dyrba, S Wolfsgruber, A Polcher… - NeuroImage: Clinical, 2021 - Elsevier
Background Cognitive decline has been found to be associated with gray matter atrophy
and disruption of functional neural networks in Alzheimer's disease (AD) in structural and …

Integration of cognitive tests and resting state fMRI for the individual identification of mild cognitive impairment

L Beltrachini, MD Marco, ZA Taylor… - Current Alzheimer …, 2015 - ingentaconnect.com
Background: Resting-state functional magnetic resonance imaging (RS-fMRI) appears as a
promising imaging technique to identify early biomarkers of Alzheimer type …

Hippocampal functional connectivity in Alzheimer's disease: a resting state 7T fMRI study

L Velayudhan, S Francis, R Dury, S Paul… - International …, 2021 - cambridge.org
Among the range of neuroimaging techniques available that may provide insight into
Alzheimer's disease (AD), resting-state functional magnetic resonance imaging (rsfMRI) and …

Intrinsic functional connectivity, CSF biomarker profiles and their relation to cognitive function in mild cognitive impairment

S Matura, J Köhler, A Reif, F Fusser… - Acta …, 2020 - cambridge.org
Mild cognitive impairment (MCI) often precedes Alzheimer's Dementia (AD), and in a high
proportion of individuals affected by MCI, there are already neuropathological processes …

MRI biomarkers for Alzheimer's disease: the impact of functional connectivity in the default mode network and structural connectivity between lobes on diagnostic …

R Mohtasib, J Alghamdi, A Jobeir, A Masawi… - Heliyon, 2022 - cell.com
Background At present, clinical use of MRI in Alzheimer's disease (AD) is mostly focused on
the assessment of brain atrophy, namely in the hippocampal region. Despite this, multiple …

Grab‐AD: generalizability and reproducibility of altered brain activity and diagnostic classification in Alzheimer's disease

D Jin, P Wang, A Zalesky, B Liu, C Song… - Human Brain …, 2020 - Wiley Online Library
Alzheimer's disease (AD) is associated with disruptions in brain activity and networks.
However, there is substantial inconsistency among studies that have investigated functional …

Seeing beyond the symptoms: biomarkers and brain regions linked to cognitive decline in Alzheimer's disease

SH Hojjati, A Babajani-Feremi… - Frontiers in Aging …, 2024 - frontiersin.org
Objective Early Alzheimer's disease (AD) diagnosis remains challenging, necessitating
specific biomarkers for timely detection. This study aimed to identify such biomarkers and …

Alzheimer's disease diagnosis and biomarker analysis using resting-state functional MRI functional brain network with multi-measures features and hippocampal …

U Khatri, GR Kwon - Frontiers in aging neuroscience, 2022 - frontiersin.org
Accurate diagnosis of the initial phase of Alzheimer's disease (AD) is essential and crucial.
The objective of this research was to employ efficient biomarkers for the diagnostic analysis …