Autologous and allogeneic cardiac stem cell therapy for cardiovascular diseases

R Sanz-Ruiz, F Fernández-Avilés - Pharmacological research, 2018 - Elsevier
Stem cell therapy is one of the most promising therapeutic innovations to help restore
cardiac structure and function after ischemic insults to the heart. However, phase I and II …

Cardiac stem cells and their roles in myocardial infarction

J Hou, L Wang, J Jiang, C Zhou, T Guo… - Stem Cell Reviews and …, 2013 - Springer
Myocardial infarction leads to loss of cardiomyocytes, scar formation, ventricular remodeling
and eventually deterioration of heart function. Over the past decade, stem cell therapy has …

Autologous cell‐based therapy for ischemic heart disease: clinical evidence, proposed mechanisms of action, and current limitations

EC Perin, GV Silva - Catheterization and Cardiovascular …, 2009 - Wiley Online Library
Cell‐based therapy is a promising approach for cardiac repair in patients with coronary
artery disease. In preclinical and early clinical studies, investigators have preliminary …

Local activation of cardiac stem cells for post‐myocardial infarction cardiac repair

Z Wen, Z Mai, H Zhang, Y Chen, D Geng… - Journal of cellular …, 2012 - Wiley Online Library
The prognosis of patients with myocardial infarction (MI) and resultant chronic heart failure
remains extremely poor despite continuous advancements in optimal medical therapy and …

[PDF][PDF] New concepts in cardiac stem cell therapy

W Wojakowski, M Tendera - Hellenic J Cardiol, 2010 - researchgate.net
and expanded in culture to be used for myocardial repair. 5 Application of CSC in
experimental acute MI reduced LV remodeling, improved contractility and reduced the infarct …

Stem cells as therapy for cardiac disease—a review

K Jezierska-Woźniak, D Mystkowska… - Folia Histochemica …, 2011 - journals.viamedica.pl
Acute myocardial infarction (AMI) is one of the most significant causes of morbidity and
mortality worldwide. Stem cells represent an enormous chance to rebuild damaged heart …

Cardiovascular stem cells in regenerative medicine: ready for prime time?

YH Liu, R Karra, SM Wu - Drug Discovery Today: Therapeutic Strategies, 2008 - Elsevier
Restoration of cardiovascular function is the ultimate goal of stem-cell-based therapy. In
principle, cardiovascular stem cells can improve cardiac function via de novo …

Stem cell-based therapies in ischemic heart diseases: a focus on aspects of microcirculation and inflammation

J Wu, J Li, N Zhang, C Zhang - Basic research in cardiology, 2011 - Springer
Stem cells possessing the potential to replace damaged myocardium with functional
myocytes have drawn increasing attention in the past decade in treating ischemic heart …

Cell therapy for ischaemic heart disease: focus on the role of resident cardiac stem cells

SAJ Chamuleau, KR Vrijsen, DG Rokosh… - Netherlands Heart …, 2009 - Springer
Myocardial infarction results in loss of cardiomyocytes, scar formation, ventricular
remodelling, and eventually heart failure. In recent years, cell therapy has emerged as a …

Cardiac stem cell therapy: review of the native cardiac progenitor cells and future direction

J Ye, Y Yeghiazarians - Journal of cardiovascular pharmacology, 2014 - journals.lww.com
Various stem cell types have been tested for regenerating damaged myocardium after
myocardial infarction. However, the results of clinical trials have not been consistent, with …