The nuclear pore complex (NPC) is a highly conserved channel in the nuclear envelope that
mediates mRNA export to the cytosol and bidirectional protein transport. Many chromosomal …

Nuclear pore complexes (NPCs) composed of∼ 30 individual nucleoporins form huge
macromolecular assemblies in the nuclear envelope, through which bidirectional cargo …

The nuclear pore complex (NPC) plays a critical role in gene expression by mediating import
of transcription regulators into the nucleus and export of RNA transcripts to the cytoplasm …

The nuclear pore complex (NPC) is a massive nuclear envelope-embedded protein
complex, the canonical function of which is to mediate selective nucleocytoplasmic transport …

Within the nucleus, chromatin is functionally organized into distinct nuclear compartments.
The nuclear periphery, containing Nuclear Pore Complexes (NPCs), plays an important role …

Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes to form
channels across the nuclear envelope. They are large macromolecular assemblies with a …

Highlights•Nuclear pore complexes and nucleoporins have many transport-independent
functions.•Nuclear pore complexes play key roles in gene expression regulation.•In yeast …

Nuclear pore complexes (NPCs), the channels connecting the nucleus with the cytoplasm,
are the largest protein structures of the nuclear envelope. In addition to their role in …

The nuclear pore complex (NPC) is the massive protein assembly that regulates the
transport of macromolecules between the nucleus and the cytoplasm. Recent breakthroughs …

Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs) whose
complex architecture is generated from a set of only∼ 30 proteins, termed nucleoporins …