Nuclear pore complexes (NPCs) are large macromolecular assemblies that control all
transport across the nuclear envelope. They are formed by about 30 nucleoporins (Nups) …

Nuclear pore complexes (NPCs) are the only transport channels that cross the nuclear
envelope. Constructed from~ 500–1000 nucleoporin proteins each, they are among the …

Exchange of macromolecules between the nucleus and cytoplasm is a key regulatory event
in the expression of a cell's genome. This exchange requires a dedicated transport …

Nuclear pore complexes (NPCs) are the sole mediators of transport between the nucleus
and the cytoplasm. NPCs have a life cycle: they assemble, disassemble, turnover, and age …

Nuclear pore complexes have recently been shown to play roles in gene activation; however
their potential involvement in metazoan transcription remains unclear. Here we show that …

Nuclear pore complexes (NPCs) facilitate macromolecular exchange between the nucleus
and cytoplasm of eukaryotic cells. The vertebrate NPC is composed of∼ 30 different …

Nuclear pore complexes play a central role in controlling the traffic between the nucleus and
the cytoplasm. Progress during the last decade has highlighted nuclear periphery …

Nuclear pore complexes (NPCs) are indispensable for cell function and are at the center of
several human diseases. NPCs provide access to the nucleus and regulate the transport of …

Nuclear pore complexes (NPCs) are large proteinaceous channels embedded in the
nuclear envelope (NE), through which exchange of molecules between the nucleus and …

Nuclear pore complexes (NPCs) govern macromolecular transport between the nucleus and
cytoplasm and serve as key positional markers within the nucleus. Several protein …