Evaluation of lung epithelial permeability

MI Newhouse, M Jordana, M Dolovich - European Journal of Nuclear …, 1987 - Springer
During the last few years a number of factors affecting the measurement of the rate of
absorption of 99m Tc-DTPA across the alveolar-capillary membrane have been identified …

Extrapulmonary radioactivity in lung permeability measurements.

G Coates, H O'Brodovich - Journal of Nuclear Medicine: Official …, 1987 - europepmc.org
The pulmonary clearance rate of aerosolized and deposited [99mTc] DTPA is used to
assess pulmonary epithelial permeability to solutes. To evaluate whether it is necessary to …

Clinical studies of alveolar-capillary permeability using technetium-99m DTPA aerosol

FX Sundram - Annals of nuclear medicine, 1995 - Springer
Soluble radioaerosols such as technetium-99m diethylene triamine pentacetate (DTPA)
permit simple quantitative studies of alveolar-capillary permeability to be performed, since …

Measurement of pulmonary epithelial permeability with 99mTc-DTPA aerosol

G Coates, H O'Brodovich - Seminars in nuclear medicine, 1986 - Elsevier
The rate at which inhaled aerosol of 99m Tc-diethylenetriamine pentacetate (DTPA) leaves
the lung by diffusion into the vascular space can be measured with a gamma camera or …

Bronchial and Alveolar Absorption of Inhaled 99mTc-DTPA

G Oberdörster, MJ Utell, PE Morrow… - American Review of …, 1986 - atsjournals.org
The clearance rate of 99mTc-DTPA deposited in the lung by inhalation has been used as an
index to measure lung epithelial permeability. To determine if differences exist between …

Determination of the mean transit time for the transport of aerosolized 99mTc‐DTPA across the pulmonary epithelial membrane. A plasma sample method

S Groth, NA Lassen, N Rossing - Clinical Physiology, 1988 - Wiley Online Library
During the last decade it has been customary to estimate pulmonary epithelial permeability
(P‐P) as the pulmonary clearance of inhaled nebulized 99mTc‐DTPA from a time‐activity (t …

A comparison of three methods of measuring 99mTc-DTPA lung clearance and their repeatability

D Morrison, K Skwarski, AM Millar… - European …, 1998 - Eur Respiratory Soc
The lung clearance of technetium-99m diethylenetriamine penta-acetic acid (99mTc-DTPA)
is a measure of respiratory epithelial permeability. Many factors may contribute to the wide …

The relative permeabilities of human conducting and terminal airways to 99mTcDTPA.

MP Barrowcliffe, JG Jones, JE Agnew… - European Journal of …, 1987 - europepmc.org
The anatomy and physiology of the pulmonary epithelial barrier are briefly described, and
methods of measuring permeability of the barrier to solutes are outlined, including findings …

Dynamic pulmonary scintigraphy with Tc99m radioaerosol for the evaluation of the permeability of the alveolo-capillary barrier

CL Maini, MG Bonetti, A Giordano, R Pistelli… - La Radiologia …, 1987 - europepmc.org
Pulmonary clearance of small droplet 99mTc-DTPA radioaerosol was studied in 100
patients (12 normal subjects, N; 10 asymptomatic healthy smokers, FA; 31 patients with …

The clearance rate of alveolar epithelium using 99mTc-DTPA in patients with diffuse infiltrative lung diseases

S Uh, SM Lee, HT Kim, Y Chung, YH Kim, CS Park - Chest, 1994 - Elsevier
The early diagnosis of diffuse infiltrative lung disease (DILD) is important in prognosis and it
is necessary to develop a noninvasive, inexpensive, and rapid diagnostic tool for suspected …