MicroRNAs (miRNAs) consist of a growing class of non-coding RNAs (ncRNAs) that
negatively regulate the expression of genes involved in development, differentiation …

Developing microRNA therapeutics for neurological diseases is both a promising
opportunity and an extremely challenging topic for several reasons. The promise stems from …

Stroke is one of the leading causes of death and disability worldwide. In past decades,
researchers have studied the physiopathology and biochemistry of stroke, but knowledge of …

In the past decade, we have witnessed considerable developments in understanding the
roles and functions of miRNAs. In parallel, the identification of alterations in miRNA …

Amyotrophic lateral sclerosis (ALS) causes neurodegeneration of both upper and lower
motor neurons and progressive muscle impairment, atrophy and death within approximately …

Remarkable advances in understanding the role of RNA in health and disease have
expanded considerably in the last decade. RNA is becoming an increasingly important …

The degeneration of substantia nigra (SN) dopamine (DA) neurons in sporadic Parkinson׳ s
disease (PD) is characterized by disturbed gene expression networks. Micro (mi) RNAs are …

Parkinson's disease (PD) is the second-most-frequent neurodegenerative disorder
worldwide. One major hallmark of PD is the degeneration of dopaminergic (DA) neurons in …

The microRNA (miRNA) class of non-coding RNAs exhibit a diverse range of regulatory
roles in neuronal functions that are conserved from lower vertebrates to primates. Disruption …

miRNAs are small noncoding RNAs that control gene expression at the posttranscriptional
level. It has been recognised that miRNA dysregulation reflects the state and function of cells …