Dose-dependent effects of phytoestrogens on bone

ZC Dang, C Lowik - Trends in Endocrinology & Metabolism, 2005 - cell.com
Phytoestrogens have the potential to maintain bone health and delay or prevent
osteoporosis. This review focuses on their dose-dependent effects on bone and their …

Soy phytoestrogens: impact on postmenopausal bone loss and mechanisms of action

RC Poulsen, MC Kruger - Nutrition Reviews, 2008 - academic.oup.com
Due to their ability to mimic the actions of mammalian estrogens, soy phytoestrogens have
been proposed as potential therapeutic agents to aid in preventing postmenopausal bone …

[HTML][HTML] Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies

KDR Setchell, E Lydeking-Olsen - The American journal of clinical nutrition, 2003 - Elsevier
Impressive data from the many studies on cultured bone cells and rat models of
postmenopausal osteoporosis support a significant bone-sparing effect of the soy …

Systematic review and meta-analysis of the bone protective effect of phytoestrogens on osteoporosis in ovariectomized rats

S Fu, G Zeng, S Zong, Z Zhang, B Zou, Y Fang, L Lu… - Nutrition Research, 2014 - Elsevier
Phytoestrogens are candidate drugs for the treatment of osteoporosis. Many experiments
have been designed to investigate the preventive effects of phytoestrogens for osteoporosis; …

Phytoestrogens—mechanism of action and effect on bone markers and bone mineral density

LA Fitzpatrick - Endocrinology and Metabolism Clinics, 2003 - endo.theclinics.com
Dietary supplements, especially those containing phytoestrogens, are frequently used to
either promote health or prevent disease. An estimated twenty billion dollars was spent on …

Estrogen and the skeleton

S Khosla, MJ Oursler, DG Monroe - Trends in Endocrinology & Metabolism, 2012 - cell.com
Estrogen is the major hormonal regulator of bone metabolism in women and men.
Therefore, there is considerable interest in unraveling the pathways by which estrogen …

Effects of phytoestrogens and other plant-derived compounds on mesenchymal stem cells, bone maintenance and regeneration

T Schilling, R Ebert, N Raaijmakers, N Schütze… - The Journal of steroid …, 2014 - Elsevier
Phytoestrogens and other plant-derived compounds and extracts have been developed for
the treatment of menopause-related complaints and disorders, eg hot flushes and …

Minireview: osteoprotective action of estrogens is mediated by osteoclastic estrogen receptor-α

Y Imai, S Kondoh, A Kouzmenko… - Molecular …, 2010 - academic.oup.com
The osteoprotective action of estrogen in women has drawn considerable attention because
estrogen deficiency-induced osteoporosis became one of the most widely spread diseases …

[HTML][HTML] Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

PA Jayusman, NS Nasruddin, B Baharin… - Frontiers in …, 2023 - frontiersin.org
Osteoporosis and periodontitis are two major chronic diseases of postmenopausal women.
The association between these two diseases are evident through systemic bone loss and …

Phyto-oestrogens and bone health: Symposium on 'Diet and bone health'

V Coxam - Proceedings of the Nutrition Society, 2008 - cambridge.org
As oestrogen deficiency is the main cause in the pathogenesis of osteoporosis hormone-
replacement therapy remains the mainstay for prevention. However, prophylaxis by …