Anti-proliferative activity of nitroquinolone fused acylhydrazones as non-small cell human lung cancer agents

V Nandakumar, A Sundarasamy… - RSC Medicinal …, 2023 - pubs.rsc.org
A new series of 8-nitroquinolone-based aromatic heterocyclic acyl hydrazones have been
synthesised and characterised through various spectroscopic techniques. They were …

Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of 4‐Nitrobenzohydrazide Derivatives as Potential Anticancer Agents

VP Sajjan, PM Gurubasavaraj, D Patil… - …, 2023 - Wiley Online Library
A series of new acylhydrazone derivatives were synthesized from the condensation of
different substituted salicylaldehydes with 4‐nitrobenzohydrazide at a molar ratio of 1: 1 in a …

Novel N-Acyl Hydrazone Compounds as Promising Anticancer Agents: Synthesis and Molecular Docking Studies

Y Biliz, B Hasdemir, H Başpınar Küçük… - ACS …, 2023 - ACS Publications
In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …

Anticancer, antimicrobial activities of quinoline based hydrazone analogues: Synthesis, characterization and molecular docking

KD Katariya, SR Shah, D Reddy - Bioorganic chemistry, 2020 - Elsevier
Based on the biologically active heterocycle quinoline, a series (18a-p) of quinoline
hydrazone analogues were prepared, starting from 6-bromo/6-chloro-2-methyl-quinolin-4-yl …

Synthesis, biological evaluation, drug-likeness, and in silico screening of novel benzylidene-hydrazone analogues as small molecule anticancer agents

MS Alam, DU Lee - Archives of pharmacal research, 2016 - Springer
A series of fifteen benzylidene-hydrazone analogues (3a–o), including eight new
compounds, were synthesized and evaluated for their cytotoxic activities in four human …

Design, Synthesis, and In Vitro Antiproliferative Screening of New Hydrazone Derivatives Containing cis-(4-Chlorostyryl) Amide Moiety

T Al-Warhi, LS Alqahtani, M Abualnaja, S Beigh… - Symmetry, 2022 - mdpi.com
Hydrazones are regarded as a distinctive category of organic compounds because of their
tremendous characteristics and potential uses in analytical, chemical, and medicinal …

New2-((2-(2,4-dinitrophenyl)hydrazineeylidene) derivatives: design, synthesis, in silico, and in vitro anticancer studies

VP Sajjan, LB Anigol, PM Gurubasavaraj… - Journal of …, 2023 - Taylor & Francis
A series of novel hydrazone compounds have been synthesized by the condensation of
hydrazines and different substituted salicylaldehydes at a molar ratio of 1: 1 in one step …

New class of potent antitumor acylhydrazone derivatives containing furan

Z Cui, Y Li, Y Ling, J Huang, J Cui, R Wang… - European journal of …, 2010 - Elsevier
A pair of chemical isomeric structures of N-acylhydrazone compounds I and II were
designed and synthesized. The reaction was carried out with high diastereoselectivity to …

Design and drug-like properties of new 5-methoxysalicylaldehyde based hydrazones with anti-breast cancer activity

B Nikolova-Mladenova, G Momekov, D Ivanov… - Journal of Applied …, 2017 - Elsevier
Novel benzoylhydrazones were designed and synthesized by condensation of 5-
methoxysalicylaldehyde and benzhydrazides with different substituents at 4th position. The …

Synthesis and characterization of novel hydrazone derivatives of isonicotinic hydrazide and their evaluation for antibacterial and cytotoxic potential

MA Shah, A Uddin, MR Shah, I Ali, R Ullah, PA Hannan… - Molecules, 2022 - mdpi.com
Hydrazones are active compounds having an azomethine–NHN= CH group and are widely
studied owing to their ease of preparation and diverse pharmacological benefits. Novel …