Plasmodium vivax treatments: what are we looking for?

RN Price, NM Douglas, NM Anstey… - Current opinion in …, 2011 - journals.lww.com
In regions coendemic for P. vivax and P. falciparum, a unified treatment policy for malaria of
any parasitological cause is likely to confer the greatest individual and public health benefit …

Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b …

A Llanos-Cuentas, MV Lacerda, R Rueangweerayut… - The Lancet, 2014 - thelancet.com
Background Clinical effectiveness of previous regimens to treat Plasmodium vivax infection
have been hampered by compliance. We aimed to assess the dose–response, safety, and …

[HTML][HTML] Costs and cost-effectiveness of Plasmodium vivax control

MT White, S Yeung, E Patouillard… - The American journal of …, 2016 - ncbi.nlm.nih.gov
The continued success of efforts to reduce the global malaria burden will require sustained
funding for interventions specifically targeting Plasmodium vivax. The optimal use of limited …

[HTML][HTML] Epidemiology and control of Plasmodium vivax in Afghanistan

T Leslie, S Nahzat, W Sediqi - The American journal of tropical …, 2016 - ncbi.nlm.nih.gov
Around half of the population of Afghanistan resides in areas at risk of malaria transmission.
Two species of malaria (Plasmodium vivax and Plasmodium falciparum) account for a high …

[HTML][HTML] Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

WRJ Taylor, K Thriemer, L von Seidlein, P Yuentrakul… - The Lancet, 2019 - thelancet.com
Background Primaquine is the only widely used drug that prevents Plasmodium vivax
malaria relapses, but adherence to the standard 14-day regimen is poor. We aimed to …

Primaquine treatment and relapse in Plasmodium vivax malaria

K Rishikesh, K Saravu - Pathogens and Global Health, 2016 - Taylor & Francis
The relapsing peculiarity of Plasmodium vivax is one of the prime reasons for sustained
global malaria transmission. Global containment of P. vivax is more challenging and crucial …

[HTML][HTML] Chloroquine–primaquine versus chloroquine alone to treat vivax malaria in Afghanistan: an open randomized superiority trial

GR Awab, M Imwong, G Bancone… - The American Journal …, 2017 - ncbi.nlm.nih.gov
Afghanistan's national guidelines recommend primaquine (PQ) for radical treatment of
Plasmodium vivax malaria, but this is rarely implemented because of concerns over …

Comparison of the Cumulative Efficacy and Safety of Chloroquine, Artesunate, and Chloroquine-Primaquine in Plasmodium vivax Malaria

CS Chu, AP Phyo, KM Lwin, HH Win… - Clinical Infectious …, 2018 - academic.oup.com
Background Chloroquine has been recommended for Plasmodium vivax infections for> 60
years, but resistance is increasing. To guide future therapies, the cumulative benefits of …

Diagnosis and treatment of Plasmodium vivax malaria

JK Baird, JD Maguire, RN Price - Advances in parasitology, 2012 - Elsevier
Infection by Plasmodium vivax poses unique challenges for diagnosis and treatment.
Relatively low numbers of parasites in peripheral circulation may be difficult to confirm, and …

[HTML][HTML] Mass primaquine treatment to eliminate vivax malaria: lessons from the past

A Kondrashin, AM Baranova, EA Ashley, J Recht… - Malaria journal, 2014 - Springer
Recent successes in malaria control have put malaria eradication back on the public health
agenda. A significant obstacle to malaria elimination in Asia is the large burden of …