Immune signature driven by ADT-induced immune microenvironment remodeling in prostate cancer is correlated with recurrence-free survival and immune infiltration
X Long, H Hou, X Wang, S Liu, T Diao, S Lai… - Cell death & …, 2020 - nature.com
Androgen deprivation therapy (ADT) is a cornerstone treatment for locally advanced or
metastatic prostate cancer (PCa). However, its potential effects on the tumor immune …
metastatic prostate cancer (PCa). However, its potential effects on the tumor immune …
Immune microenvironment and response in prostate cancer using large population cohorts
X Ren, X Chen, X Zhang, S Jiang, T Zhang… - Frontiers in …, 2021 - frontiersin.org
Immune microenvironment of prostate cancer (PCa) is implicated in disease progression.
However, previous studies have not fully explored PCa immune microenvironment. This …
However, previous studies have not fully explored PCa immune microenvironment. This …
A novel immune-related gene-based prognostic signature to predict biochemical recurrence in patients with prostate cancer after radical prostatectomy
D Lv, X Wu, X Chen, S Yang, W Chen, M Wang… - Cancer Immunology …, 2021 - Springer
Accumulating evidences indicates that the immune landscape signature dramatically
correlates with tumorigenesis and prognosis of prostate cancer (PCa). Here, we identified a …
correlates with tumorigenesis and prognosis of prostate cancer (PCa). Here, we identified a …
Immune microenvironment infiltration landscape and immune-related subtypes in prostate cancer
W Wu, X Wang, W Le, C Lu, H Li, Y Zhu… - Frontiers in …, 2023 - frontiersin.org
Background The tumor microenvironment (TME) primarily comprises cancer cells, cancer-
infiltrating immune cells, and stromal cells. The tumor cells alter the TME by secreting …
infiltrating immune cells, and stromal cells. The tumor cells alter the TME by secreting …
Prognostic value of genes and immune infiltration in prostate tumor microenvironment
W Sun, H Shi, Z Yuan, L Xia, X Xiang, X Quan… - Frontiers in …, 2020 - frontiersin.org
Background Prostate cancer (PCa) is one of the most common cancers and the fifth leading
cause of cancer-related death in men. Immune responses in the tumor microenvironment …
cause of cancer-related death in men. Immune responses in the tumor microenvironment …
Immunosuppressive environment in response to androgen deprivation treatment in prostate cancer
C Qin, J Wang, Y Du, T Xu - Frontiers in Endocrinology, 2022 - frontiersin.org
Rationale To invest the role of androgen deprivation therapy (ADT) on the tumor immune
microenvironment of prostate cancer. Methods Here we have profiled the transcriptomes of …
microenvironment of prostate cancer. Methods Here we have profiled the transcriptomes of …
[HTML][HTML] Identification of biomarkers for immunotherapy response in prostate cancer and potential drugs to alleviate immunosuppression
J Zhang, X Ding, K Peng, Z Jia, J Yang - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Background: Immunotherapy has a significant effect on the treatment of many tumor types.
However, prostate cancers generally fail to show significant responses to immunotherapy …
However, prostate cancers generally fail to show significant responses to immunotherapy …
Immune-related genes are prognostic markers for prostate cancer recurrence
M Fu, Q Wang, H Wang, Y Dai, J Wang, W Kang… - Frontiers in …, 2021 - frontiersin.org
Background Prostate cancer (PCa) is an immune-responsive disease. The current study
sought to explore a robust immune-related prognostic gene signature for PCa. Methods …
sought to explore a robust immune-related prognostic gene signature for PCa. Methods …
Developing an immune‐related gene prognostic index associated with progression and providing new insights into the tumor immune microenvironment of prostate …
D Feng, F Zhang, D Li, X Shi, Q Xiong, Q Wei… - …, 2022 - Wiley Online Library
We developed an immune‐related gene prognostic index (IGPI) associated with progression
and provided new insights into the tumour immune microenvironment (TIME) for prostate …
and provided new insights into the tumour immune microenvironment (TIME) for prostate …
Immune response drives outcomes in prostate cancer: Implications for immunotherapy
The heterogeneity of the immune microenvironment leads to different responses in immune
checkpoint blockade therapy. We aimed to propose a robust molecular classification system …
checkpoint blockade therapy. We aimed to propose a robust molecular classification system …
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