Androgen deprivation therapy (ADT) is a cornerstone treatment for locally advanced or
metastatic prostate cancer (PCa). However, its potential effects on the tumor immune …

Immune microenvironment of prostate cancer (PCa) is implicated in disease progression.
However, previous studies have not fully explored PCa immune microenvironment. This …

Accumulating evidences indicates that the immune landscape signature dramatically
correlates with tumorigenesis and prognosis of prostate cancer (PCa). Here, we identified a …

Background The tumor microenvironment (TME) primarily comprises cancer cells, cancer-
infiltrating immune cells, and stromal cells. The tumor cells alter the TME by secreting …

Background Prostate cancer (PCa) is one of the most common cancers and the fifth leading
cause of cancer-related death in men. Immune responses in the tumor microenvironment …

Rationale To invest the role of androgen deprivation therapy (ADT) on the tumor immune
microenvironment of prostate cancer. Methods Here we have profiled the transcriptomes of …

Background The tumor microenvironment (TME) has recently been proven to play a crucial
role in the development and prognosis of tumors. However, the current knowledge on the …

Background Prostate cancer (PCa) is an immune-responsive disease. The current study
sought to explore a robust immune-related prognostic gene signature for PCa. Methods …

Background: Immunotherapy has a significant effect on the treatment of many tumor types.
However, prostate cancers generally fail to show significant responses to immunotherapy …

We developed an immune‐related gene prognostic index (IGPI) associated with progression
and provided new insights into the tumour immune microenvironment (TIME) for prostate …