Basement membrane plays an important role in tumor invasion and metastasis, which is
closely related to prognosis. However, the prognostic value and biology of basement …

Prostate cancer is the most commonly diagnosed cancer but the management of advanced
prostate cancer remains a therapeutic challenge, despite the survival benefits imparted by …

Cuproptosis, Copper Induced Cell Death, is a newly defined type of programmed cell death,
involving in the regulation of tricarboxylic acid (TCA) cycle. Dysfunction of cuproptosis …

Background In immunosurveillance, bone‐derived immune cells infiltrate the tumor and
secrete inflammatory cytokines to destroy cancer cells. However, cancer cells have evolved …

Simple Summary The mainstay of treatment for advanced prostate cancer (PCa) is androgen
deprivation therapy (ADT), and although patients initially respond, almost all will eventually …

Background: Prostate cancer is usually considered as immune “cold” tumor with poor
immunogenic response and low density of tumor-infiltrating immune cells, highlighting the …

Prostate cancer is still a significant global health burden in the coming decade. Novel
biomarkers for detection and prognosis are needed to improve the survival of distant and …

Background Prostate cancer (PCa) is the most common malignant tumor in men. Although
clinical treatments of PCa have made great progress in recent decades, once tolerance to …

Purpose: Patients with neuroendocrine prostate cancer (NEPC) are often managed with
immunotherapy regimens extrapolated from small-cell lung cancer (SCLC). We sought to …

Purpose: The role of immune-oncologic mechanisms of racial disparities in prostate cancer
remains understudied. Limited research exists to evaluate the molecular underpinnings of …