Digital droplet PCR at the time of TKI discontinuation in chronic‐phase chronic myeloid
leukemia patients is predictive of treatment‐free remission outcome-Colafigli-2019 …

Background The monitoring of BCR-ABL transcript levels by real-time quantitative
polymerase chain reaction (RT-qPCR) has become important to assess minimal residual …

The unique molecular characteristic of chronic myeloid leukemia (CML), the disease-
causing ABL (9q34) to BCR (22q11) translocation, has provided an invaluable tool for …

We read with great interest the article by Kjaer et al.[1] aiming at investigating the
performance of a standardized qPCR assay in quantification of BCR-ABL1 transcripts in …

Chronic myeloid leukemia (CML) is a clonal malignant disorder of a pluripotent
hematopoietic stem cell characterized by the presence of the reciprocal translocation t (9; …

We describe a new flow‐cytometric analysis using quadruple labelling with anti‐CD19,
CD20, CD5, CD79b monoclonal antibodies and sequential gating. We determined a novel …

For the diagnosis of CML and for monitoring of treatment response the detection of the t (9;
22)(q34; q11) or the BCR-ABL rearrangement is necessary. Chromosome banding analysis …

BACKGROUND AND OBJECTIVES: The limited value of qualitative reverse transcription
polymerase chain-reaction (RT-PCR) for monitoring chronic myeloid leukemia (CML) …

Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 fusion protein, encoded by the
Philadelphia chromosome, have drastically improved the outcomes for patients with chronic …

Abstract Background: BCR-ABL fusion mRNA expression in bone marrow or peripheral
blood can be used as a measure of minimal residual disease in patients with chronic …