Thyroid hormones as modulators of immune activities at the cellular level

P De Vito, S Incerpi, JZ Pedersen, P Luly, FB Davis… - Thyroid, 2011 - liebertpub.com
Background: Increasing evidence suggests that thyroid hormones, L-thyroxine (T4) and 3,
3′, 5-triiodo-L-thyronine (T3), are modulators of the immune response. In monocytes …

[HTML][HTML] Thyroid hormone action on innate immunity

MM Montesinos, CG Pellizas - Frontiers in endocrinology, 2019 - frontiersin.org
The interplay between thyroid hormone action and the immune system has been
established in physiological and pathological settings. However, their connection is complex …

The interplay of thyroid hormones and the immune system–where we stand and why we need to know about it

C Wenzek, A Boelen, AM Westendorf… - European journal of …, 2022 - academic.oup.com
Over the past few years, growing evidence suggests direct crosstalk between thyroid
hormones (THs) and the immune system. Components of the immune system were …

Nongenomic effects of thyroid hormones on the immune system cells: new targets, old players

P De Vito, V Balducci, S Leone, Z Percario, G Mangino… - Steroids, 2012 - Elsevier
It is now widely accepted that thyroid hormones, l-thyroxine (T4) and 3, 3′, 5-triiodo-l-
thyronine (T3), act as modulators of the immune response. Immune functions such as …

Modulating the function of the immune system by thyroid hormones and thyrotropin

EL Jara, N Muñoz-Durango, C Llanos, C Fardella… - Immunology letters, 2017 - Elsevier
Accumulating evidence suggests a close bidirectional communication and regulation
between the neuroendocrine and immune systems. Thyroid hormones (THs) can exert …

[HTML][HTML] Thyroid hormones interaction with immune response, inflammation and non-thyroidal illness syndrome

R De Luca, PJ Davis, HY Lin, F Gionfra… - Frontiers in cell and …, 2021 - frontiersin.org
The interdependence between thyroid hormones (THs), namely, thyroxine and
triiodothyronine, and immune system is nowadays well-recognized, although not yet fully …

The pathogenesis of thyroid autoimmune diseases: new T lymphocytes–cytokines circuits beyond the Th1− Th2 paradigm

Q Li, B Wang, K Mu, JA Zhang - Journal of Cellular Physiology, 2019 - Wiley Online Library
Autoimmune thyroid disease (AITD) is one of the most common organ‐specific autoimmune
disorders. It mainly manifests as Hashimoto's thyroiditis (HT) and Graves' disease (GD). HT …

[HTML][HTML] A role for iodide and thyroglobulin in modulating the function of human immune cells

MY Bilal, S Dambaeva, J Kwak-Kim… - Frontiers in …, 2017 - frontiersin.org
Iodine is an essential element required for the function of all organ systems. Although the
importance of iodine in thyroid hormone synthesis and reproduction is well known, its direct …

The immune system as a regulator of thyroid hormone activity

JR Klein - Experimental Biology and Medicine, 2006 - journals.sagepub.com
It has been known for decades that the neuroendocrine system can both directly and
indirectly influence the developmental and functional activity of the immune system. In …

[HTML][HTML] The thyroid hormone triiodothyronine controls macrophage maturation and functions: protective role during inflammation

C Perrotta, M Buldorini, E Assi, D Cazzato… - The American Journal of …, 2014 - Elsevier
The endocrine system participates in regulating macrophage maturation, although little is
known about the modulating role of the thyroid hormones. In vitro results demonstrate a …