The results of immunotherapy and immunopathologic studies are described in a patient with
nucleoside phosphorylase deficiency, normal B cell function, and severe absence of T cell …

Biological and immunological studies were performed on a child with severely impaired T-
cell function, normal B-cell function, and deficiency of nucleoside phosphorylase. Adenosine …

Immune function in two brothers with a deficiency of purine nucleoside phosphorylase was
evaluated in vivo and in vitro. Both patients had a history of recurrent infections and …

Purine nucleoside phosphorylase deficiency in association with immunodeficiency is a
distinctive immunological disorder. A total of nine patients, in six different institutions, have …

A 2 1/2-year-old boy presented with an illness resembling glandular fever. He was found to
have T-cell deficiency with lack of red and white cell purine nucleoside phosphorylase …

We describe a 2 year old girl with nucleoside phosphorylase (PNP) deficiency, who had low
blood T cell numbers and T lymphocyte blastogenic response to mitogens …

Purine nucleoside phosphorylase (PNP) deficiency is a rare inherited disease accounting
for approximately 4% of patients with severe combined immunodeficiency. Thirty-three …

We studied a 15-month-old girl who had normal T-cell and B-cell immunity at birth, after
which a gradual decrease in T-cell immunity developed. This selective cellular …

Two brothers, age 9 and 11, respectively, have marked deficiency of nucleoside
phosphorylase associated with defective T-cell function and normal B-cell function. Unlike …

Purine-nucleoside phosphorylase (NP) deficiency is associated with severely defective
thymus-derived (T)-cell and normally functioning bone marrow-derived (B)-cell immunity. In …