[HTML][HTML] In silico identification and characterization of promising drug targets in highly virulent uropathogenic Escherichia coli strain CFT073 by protein-protein …

H Kaur, M Kalia, V Singh, V Modgil, B Mohan… - Informatics in Medicine …, 2021 - Elsevier
Urinary tract infections (UTIs) are one of the commonest bacterial infections worldwide. The
most common etiological agent is uropathogenic Escherichia coli. The occurrence of high …

Identification and functional annotation of hypothetical proteins of uropathogenic Escherichia coli strain CFT073 towards designing antimicrobial drug targets

H Kaur, V Singh, M Kalia, B Mohan… - Journal of Biomolecular …, 2022 - Taylor & Francis
Urinary tract infections are a serious health concern worldwide, especially in developing
countries. Escherichia coli strain CFT073 is a highly virulent pathogenic bacterial strain …

In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii

E Zadeh Hosseingholi, G Zarrini… - Microbial Drug …, 2020 - liebertpub.com
Acinetobacter baumannii is known as a Gram-negative bacterium that has become one of
the most important health problems due to antibiotic resistance. Today, numerous efforts are …

Uropathogenic bacteria and deductive genomics towards antimicrobial resistance, virulence, and potential drug targets

A Amin, R Noureen, A Iftikhar, A Hussain… - International …, 2024 - Springer
Urinary tract infections (UTIs) are among the most prevalent bacterial infections affecting
people in inpatient and outpatient settings. The current study aimed to sequence the …

Computational Guided Drug Targets Identification against Extended-Spectrum Beta-Lactamase-Producing Multi-Drug Resistant Uropathogenic Escherichia coli

H Kaur, V Modgil, N Chaudhary, B Mohan, N Taneja - Biomedicines, 2023 - mdpi.com
Urinary tract infections (UTIs) are one of the most frequent bacterial infections in the world,
both in the hospital and community settings. Uropathogenic Escherichia coli (UPEC) are the …

Computational approach towards the design of novel inhibitor against universal stress protein A to combat multidrug resistant uropathogenic Escherichia coli

D Bandyopadhyay, G Singh, M Mukherjee… - Journal of Molecular …, 2021 - Elsevier
Uropathogenic Escherichia coli is one of the primary causative agent of urinary tract
infections (UTIs), poses a threat to public health globally. Antibiotics are the only options for …

Bioinformatics analyses for the designation of a hybrid protein against urinary tract infections caused by Pseudomonas aeruginosa and investigation of the presence …

H Sharbatdaralaei, MR Asadi Karam… - Journal of …, 2022 - Taylor & Francis
Pseudomonas aeruginosa is an important pathogen causing urinary tract infections (UTIs)
and resistance to antibiotics has increased the need for a vaccine against this bacterium. P …

Genome-Wide Identification of Potential Drug Target in Enterobacteriaceae Family: A Homology-Based Method

M Hadizadeh, SN Tabatabaiepour… - Microbial Drug …, 2018 - liebertpub.com
The Enterobacteriaceae is a large family of Gram-negative, facultative anaerobic, non-spore
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …

Immunoinformatics aided designing of a next generation poly-epitope vaccine against uropathogenic Escherichia coli to combat urinary tract infections

Z Ishaq, T Zaheer, M Waseem… - Journal of …, 2023 - Taylor & Francis
Urinary tract infections (UTIs) are the second most prevalent bacterial infections and
uropathogenic Escherichia coli (UPEC) stands among the primary causative agents of UTIs …

Targeting Essential Hypothetical Proteins of Pseudomonas aeruginosa PAO1 for Mining of Novel Therapeutics: An In Silico Approach

A Rahman, MT Sarker, MA Islam… - BioMed Research …, 2023 - Wiley Online Library
As an omnipresent opportunistic bacterium, Pseudomonas aeruginosa PAO1 is responsible
for acute and chronic infection in immunocompromised individuals. Currently, this bacterium …