The classical secretory renin-a is known to be involved in angiotensin generation, thereby
regulating not only blood pressure, but also promoting oxidative stress as well as apoptotic …

The classical secretory renin-a is known to be involved in angiotensin generation, thereby
regulating not only blood pressure, but also promoting oxidative stress as well as apoptotic …

A stimulated renin-angiotensin system is known to promote oxidative stress, apoptosis,
necrosis and fibrosis. Renin transcripts (renin-b; renin-c) encoding a cytosolic renin isoform …

Although the renin-angiotensin system usually promotes oxidative stress and cell death,
renin transcripts have been discovered, whose transcription product may be …

Background/Aims: Renin is known as a secretory glycoprotein that ultimately leads to
angiotensin II generation. In this way renin exerts pro-inflammatory effects and promotes …

The renin-angiotensin system is known to regulate blood pressure as well as water-and
electrolyte balance. An activated RAS is involved in the development of hypertension and …

The renin‐angiotensin system promotes oxidative stress, apoptosis, necrosis, fibrosis, and
thus heart failure. Secretory renin plays a central role in these processes, initiating the …

In the heart, secretory renin promotes hypertrophy, apoptosis, necrosis, fibrosis, and cardiac
failure through angiotensin generation from angiotensinogen. Thus, inhibitors of the renin …

Several cardiac and renal diseases are attributed to a dysregulation of the renin-angiotensin
system. Renin, the rate-limiting enzyme of the renin-angiotensin system, has 2 isoforms. The …

Tissue accumulation of circulating prorenin results in angiotensin generation, but could also,
through binding to the recently cloned (pro) renin receptor, lead to angiotensin-independent …