Machine learning for drug-target interaction prediction
Identifying drug-target interactions will greatly narrow down the scope of search of candidate
medications, and thus can serve as the vital first step in drug discovery. Considering that in …
medications, and thus can serve as the vital first step in drug discovery. Considering that in …
Deep learning in drug target interaction prediction: current and future perspectives
Drug-target Interactions (DTIs) prediction plays a central role in drug discovery.
Computational methods in DTIs prediction have gained more attention because carrying out …
Computational methods in DTIs prediction have gained more attention because carrying out …
Machine learning approaches and databases for prediction of drug–target interaction: a survey paper
The task of predicting the interactions between drugs and targets plays a key role in the
process of drug discovery. There is a need to develop novel and efficient prediction …
process of drug discovery. There is a need to develop novel and efficient prediction …
DeepPurpose: a deep learning library for drug–target interaction prediction
Accurate prediction of drug–target interactions (DTI) is crucial for drug discovery. Recently,
deep learning (DL) models for show promising performance for DTI prediction. However …
deep learning (DL) models for show promising performance for DTI prediction. However …
Network-based methods for prediction of drug-target interactions
Drug-target interaction (DTI) is the basis of drug discovery. However, it is time-consuming
and costly to determine DTIs experimentally. Over the past decade, various computational …
and costly to determine DTIs experimentally. Over the past decade, various computational …
Comparison study of computational prediction tools for drug-target binding affinities
The drug development is generally arduous, costly, and success rates are low. Thus, the
identification of drug-target interactions (DTIs) has become a crucial step in early stages of …
identification of drug-target interactions (DTIs) has become a crucial step in early stages of …
Deep learning-based transcriptome data classification for drug-target interaction prediction
L Xie, S He, X Song, X Bo, Z Zhang - BMC genomics, 2018 - Springer
Background The ability to predict the interaction of drugs with target proteins is essential to
research and development of drug. However, the traditional experimental paradigm is costly …
research and development of drug. However, the traditional experimental paradigm is costly …
Application of machine learning for drug–target interaction prediction
L Xu, X Ru, R Song - Frontiers in genetics, 2021 - frontiersin.org
Exploring drug–target interactions by biomedical experiments requires a lot of human,
financial, and material resources. To save time and cost to meet the needs of the present …
financial, and material resources. To save time and cost to meet the needs of the present …
DASPfind: new efficient method to predict drug–target interactions
Background Identification of novel drug–target interactions (DTIs) is important for drug
discovery. Experimental determination of such DTIs is costly and time consuming, hence it …
discovery. Experimental determination of such DTIs is costly and time consuming, hence it …
Padme: A deep learning-based framework for drug-target interaction prediction
In silico drug-target interaction (DTI) prediction is an important and challenging problem in
biomedical research with a huge potential benefit to the pharmaceutical industry and …
biomedical research with a huge potential benefit to the pharmaceutical industry and …