Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides

M Haffke, A Menzel, Y Carius, D Jahn… - … Section D: Biological …, 2010 - journals.iucr.org
The human ATP-binding cassette (ABC) transporter ABCB6 is involved in haem-precursor
transport across the mitochondrial membrane. The crystal structure of its nucleotide-binding …

Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states

CA Shintre, ACW Pike, Q Li, JI Kim… - Proceedings of the …, 2013 - National Acad Sciences
ABCB10 is one of the three ATP-binding cassette (ABC) transporters found in the inner
membrane of mitochondria. In mammals ABCB10 is essential for erythropoiesis, and for …

Human ABC transporter isoform B6 (ABCB6) localizes primarily in the Golgi apparatus

M Tsuchida, Y Emi, Y Kida, M Sakaguchi - Biochemical and biophysical …, 2008 - Elsevier
Human ATP-binding cassette transporter isoform B6 (ABCB6) has been proposed to be
situated in both the inner and outer membranes of mitochondria. These inconsistent …

Structures and functions of mitochondrial ABC transporters

TA Schaedler, B Faust, CA Shintre… - Biochemical Society …, 2015 - portlandpress.com
A small number of physiologically important ATP-binding cassette (ABC) transporters are
found in mitochondria. Most are half transporters of the B group forming homodimers and …

Cryo-EM structure of human ABCB8 transporter in nucleotide binding state

S Li, Y Ren, X Lu, Y Shen, X Yang - Biochemical and Biophysical Research …, 2021 - Elsevier
Human ATP-binding cassette transporter 8 of subfamily B (hABCB8) is an ABC transporter
that located in the inner membrane of mitochondria. The ABCB8 is involved in the …

Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein

K Kiss, N Kucsma, A Brozik, GE Tusnady… - Biochemical …, 2015 - portlandpress.com
ATP-binding cassette, subfamily B (ABCB) 6 is a homodimeric ATP-binding cassette (ABC)
transporter present in the plasma membrane and in the intracellular organelles. The …

[HTML][HTML] Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me)

SA Graf, SE Haigh, ED Corson, OS Shirihai - Journal of Biological …, 2004 - ASBMB
ATP binding cassette (ABC) transporters are a diverse superfamily of energy-dependent
membrane translocases. Although responsible for the majority of transmembrane transport …

[HTML][HTML] Cryo-EM structure of cadmium-bound human ABCB6

SH Choi, SS Lee, HY Lee, S Kim, JW Kim… - Communications …, 2024 - nature.com
ATP-binding cassette transporter B6 (ABCB6), a protein essential for heme biosynthesis in
mitochondria, also functions as a heavy metal efflux pump. Here, we present cryo-electron …

Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7

Q Yan, Y Shen, X Yang - Journal of Structural Biology, 2022 - Elsevier
ATP-binding cassette subfamily B member 7 (ABCB7) is localized in the inner membrane of
mitochondria, playing a critical role in iron metabolism. Here, we determined the structure of …

Heteronuclear multidimensional NMR and homology modelling studies of the C-terminal nucleotide-binding domain of the human mitochondrial ABC transporter …

K Kurashima-Ito, T Ikeya, H Senbongi, H Tochio… - Journal of biomolecular …, 2006 - Springer
Human ATP-binding cassette, sub-family B, member 6 (ABCB6) is a mitochondrial ABC
transporter, and presumably contributes to iron homeostasis. Aimed at understanding the …