Pyroptosis: role and mechanisms in cardiovascular disease

X Chen, PC Tian, K Wang, M Wang… - Frontiers in cardiovascular …, 2022 - frontiersin.org
Cardiovascular disease (CVD) is a common disease that poses a huge threat to human
health. Irreversible cardiac damage due to cardiomyocyte death and lack of regenerative …

Pyroptosis: a pro-inflammatory type of cell death in cardiovascular disease

Q Wang, J Wu, Y Zeng, K Chen, C Wang, S Yang… - Clinica chimica acta, 2020 - Elsevier
Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by
gasdermin D (GSDMD)-mediated membrane pore formation, cell swelling and rapid lysis …

Cardiac remodeling in heart failure: role of pyroptosis and its therapeutic implications

R Chai, W Xue, S Shi, Y Zhou, Y Du, Y Li… - Frontiers in …, 2022 - frontiersin.org
Pyroptosis is a kind of programmed cell death closely related to inflammation. The pathways
that mediate pyroptosis can be divided into the Caspase-1-dependent canonical pathway …

Therapeutic implications of targeting pyroptosis in Cardiac-related etiology of heart failure

O Habimana, OM Salami, J Peng, GH Yi - Biochemical pharmacology, 2022 - Elsevier
Heart failure remains a considerable clinical and public health problem, it is the dominant
cause of death from cardiovascular diseases, besides, cardiovascular diseases are one of …

[HTML][HTML] Pyroptosis is a drug target for prevention of adverse cardiac remodeling: The crosstalk between pyroptosis, apoptosis, and autophagy

NV Naryzhnaya, LN Maslov, SV Popov… - Journal of biomedical …, 2022 - ncbi.nlm.nih.gov
Acute myocardial infarction (AMI) is one of the main reasons of cardiovascular disease-
related death. The introduction of percutaneous coronary intervention to clinical practice …

Role of pyroptosis in atherosclerosis and its therapeutic implications

B He, Q Nie, F Wang, Y Han, B Yang… - Journal of cellular …, 2021 - Wiley Online Library
Atherosclerosis is a significant cardiovascular burden and a leading cause of death
worldwide, recognized as a chronic sterile inflammatory disease. Pyroptosis is a novel …

The role of ROS-induced pyroptosis in CVD

K Tian, Y Yang, K Zhou, N Deng, Z Tian… - Frontiers in …, 2023 - frontiersin.org
Cardiovascular disease (CVD) is the number one cause of death in the world and seriously
threatens human health. Pyroptosis is a new type of cell death discovered in recent years …

Pyroptosis: a new regulating mechanism in cardiovascular disease

N Ji, Z Qi, Y Wang, X Yang, Z Yan, M Li… - Journal of …, 2021 - Taylor & Francis
Pyroptosis is a kind of pro-inflammatory cell death. Compared with autophagy and
apoptosis, pyroptosis has unique characteristics in morphology and mechanism …

[HTML][HTML] Role of pyroptosis in cardiovascular diseases and its therapeutic implications

C Zeng, R Wang, H Tan - International journal of biological …, 2019 - ncbi.nlm.nih.gov
Pyroptotic cell death or pyroptosis is characterized by caspase-1-dependent formation of
plasma membrane pores, leading to the release of pro-inflammatory cytokines and cell lysis …

Role of pyroptosis in cardiovascular diseases

C Jia, H Chen, J Zhang, K Zhou, Y Zhuge, C Niu… - International …, 2019 - Elsevier
Pyroptosis is a form of programmed necrosis, and is morphologically and mechanistically
unique form of programmed cell death compared to others, such as apoptosis and …